Entry Detail



General Information

Database ID:LDA0003745
Species:Homo sapiens
Confidence Score:0.8785
Contents:>> ncRNA Information
>> Regulatory Relationship
>> Disease Information
>> Evidence Support
>> Reference

 

ncRNA Information

ncRNA Symbol:PCAT1
Full Name:prostate cancer associated transcript 1 (non-protein coding)
Category:lncRNA
Species:Homo sapiens
Synonyms:PCAT-1//PCA1
Chromosome:8
Strand:+
Coordinate:
Start Site(bp):126847055End Site(bp):127021014
Gene Summary:N/A
External Links:
Ensembl ID:ENSG00000253438
HGNC ID:HGNC:43022
Entrez Gene:100750225
VEGA ID:OTTHUMG00000165061
UCSC ID:uc064qdc.1
ENA:HQ605084
RefSeq Accession:NR_045262
UniProtKB:N/A

 

Regulatory Relationship

mRNA targets:N/A
miRNA targets:N/A
Display:N/A

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:4947D018281
Disease Name:cholangiocarcinomaCholangiocarcinoma
Category:Disease OntologyMeSH
Type:disease of cellular proliferationNeoplasms
Define:A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.A malignant tumor arising from the epithelium of the BILE DUCTS.
Alias:adult primary Cholangiocarcinoma//adult primary cholangiocellular carcinoma//cholangiosarcomaCholangiocarcinomas//Cholangiocellular Carcinoma//Carcinoma, Cholangiocellular//Carcinomas, Cholangiocellular//Cholangiocellular Carcinomas//Extrahepatic Cholangiocarcinoma//Cholangiocarcinoma, Extrahepatic//Cholangiocarcinomas, Extrahepatic//Extrahepatic Cholangiocarcinomas//Intrahepatic Cholangiocarcinoma//Cholangiocarcinoma, Intrahepatic//Cholangiocarcinomas, Intrahepatic//Intrahepatic Cholangiocarcinomas

 

Evidence Support

Strong Evidence:Luciferase reporter gene assay
Weak Evidence:Bioinformatic analysis
Prediction Method:N/A

 

Reference

[1] PubMed ID:28753454
Disease Name:cholangiocarcinoma
Sample:ECC tissue samples and cell lines
Dysfunction Pattern:Regulation [up-regulated]
Validated Method:Bioinformatic analysis//Luciferase reporter gene assay
Description:Previously, we showed that PCAT1 is up-regulated in both ECC tissue samples and cell lines.
Author:Zhang F,Wan M,Xu Y,Li Z,Leng K,Kang P,Cui Y,Jiang X
Year:2017
Title:Long noncoding RNA PCAT1 regulates extrahepatic cholangiocarcinoma progression via the Wnt/β-catenin-signaling pathway.
Causality:Yes