Entry Detail



General Information

Database ID:LDA0003786
Species:Homo sapiens
Confidence Score:0.8808
Contents:>> ncRNA Information
>> Regulatory Relationship
>> Disease Information
>> Evidence Support
>> Reference

 

ncRNA Information

ncRNA Symbol:SNHG5
Full Name:small nucleolar RNA host gene 5
Category:lncRNA
Species:Homo sapiens
Synonyms:MGC16362//bA33E24.2//U50HG//NCRNA00044//LINC00044
Chromosome:6
Strand:-
Coordinate:
Start Site(bp):85660950End Site(bp):85678736
Gene Summary:This gene is a member of both the non-protein-coding multiple snoRNA host gene family and the 5'-terminal oligopyrimidine (5' TOP) class of genes. Two snoRNAs are derived from the introns of this host gene but, although many alternative splice variants have been observed, the gene is thought to have no protein-coding potential. The gene is located at the chromosomal translocation breakpoint involved in B-cell lymphoma. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000203875
HGNC ID:HGNC:21026
Entrez Gene:387066
VEGA ID:OTTHUMG00000015144
UCSC ID:uc063pxm.1
ENA:BC009220
RefSeq Accession:NR_003038
UniProtKB:N/A

 

Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
SNX14
6
85505496
85594156
-
AL589666.1
6
85557978
85615234
-
SYNCRIP
6
85607785
85643792
-
miRNA targets:N/A
Display:

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:3083D029424
Disease Name:chronic obstructive pulmonary diseasePulmonary Disease, Chronic Obstructive
Category:Disease OntologyMeSH
Type:disease of anatomical entityRespiratory Tract Diseases
Define:N/AA disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.
Alias:chronic obstructive airway disease//chronic obstructive lung disease//COLD (chronic obstructive lung disease)//COPDCOPD//Chronic Obstructive Pulmonary Disease//COAD//Chronic Obstructive Airway Disease//Chronic Obstructive Lung Disease//Airflow Obstruction, Chronic//Airflow Obstructions, Chronic//Chronic Airflow Obstructions//Chronic Airflow Obstruction

 

Evidence Support

Strong Evidence:qRT-PCR//Western blot
Weak Evidence:N/A
Prediction Method:N/A

 

Reference

[1] PubMed ID:27932875
Disease Name:chronic obstructive pulmonary disease
Sample:COPD lung tissues compared with non-COPD lung tissues
Dysfunction Pattern:Expression [low expression]
Validated Method:qRT-PCR//Western blot
Description:Five of the analyzed lncRNAs (BC038205, BC130595, TUG1, MEG3, and LOC646329) were markedly increased, while five lncRNAs (LOC729178, PLAC2, LOC339529, LINC00229, and SNHG5) were significantly decreased in COPD lung tissues compared with non-COPD lung tiss__
Author:Tang W,Shen Z,Guo J,Sun S
Year:2016
Title:Screening of long non-coding RNA and TUG1 inhibits proliferation with TGF-β induction in patients with COPD.
Causality:No