Entry Detail



General Information

Database ID:LDA0003828
Species:Homo sapiens
Confidence Score:0.8808
Contents:>> ncRNA Information
>> Regulatory Relationship
>> Disease Information
>> Evidence Support
>> Reference

 

ncRNA Information

ncRNA Symbol:ZFAS1
Full Name:ZNFX1 antisense RNA 1
Category:lncRNA
Species:Homo sapiens
Synonyms:HSUP1//HSUP2
Chromosome:20
Strand:+
Coordinate:
Start Site(bp):49278178End Site(bp):49295738
Gene Summary:N/A
External Links:
Ensembl ID:ENSG00000177410
HGNC ID:HGNC:33101
Entrez Gene:441951
VEGA ID:OTTHUMG00000032698
UCSC ID:uc061xqc.1
ENA:AY513722//AY513723
RefSeq Accession:NR_003604
UniProtKB:N/A

 

Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
STAU1
20
49113339
49188367
-
DDX27
20
49219295
49244077
+
ZNFX1
20
49237946
49278426
-
KCNB1
20
49293394
49484297
-
miRNA targets:N/A
Display:

 

Disease Information

 Disease OntologyMeSH
Disease ID:D003110N/A
Disease Name:Colonic NeoplasmsN/A
Category:MeSHN/A
Type:Neoplasms//Digestive System DiseasesN/A
Define:Tumors or cancer of the COLON.N/A
Alias:Colonic Neoplasm//Neoplasm, Colonic//Neoplasms, Colonic//Colon Neoplasms//Colon Neoplasm//Neoplasm, Colon//Neoplasms, Colon//Cancer of Colon//Colon Cancers//Cancer of the Colon//Colonic Cancer//Cancer, Colonic//Cancers, Colonic//Colonic Cancers//Colon Cancer//Cancer, Colon//Cancers, ColonN/A

 

Evidence Support

Strong Evidence:Knockdown//qRT-PCR
Weak Evidence:N/A
Prediction Method:N/A

 

Reference

[1] PubMed ID:27862275
Disease Name:Colonic Neoplasms
Sample:colonic cancer tissues, cell lines, and plasma
Dysfunction Pattern:Expression [high expression]
Validated Method:qRT-PCR//Knockdown
Description:Knockdown of ZFAS1 decreased expression of ZEB1 and increased the epithelial markers E-cadherin, ZO-1 while decreasing mesenchymal markers vimentin and N-cadherin.
Author:Fang C,Zan J,Yue B,Liu C,He C,Yan D
Year:2017
Title:Long non-coding ribonucleic acid zinc finger antisense 1 promotes the progression of colonic cancer by modulating ZEB1 expression.
Causality:Yes