Entry Detail



General Information

Database ID:LDA0004189
Species:Homo sapiens
Confidence Score:0.8785
Contents:>> ncRNA Information
>> Regulatory Relationship
>> Disease Information
>> Evidence Support
>> Reference

 

ncRNA Information

ncRNA Symbol:LINC01233
Full Name:long intergenic non-protein coding RNA 1233
Category:lncRNA
Species:Homo sapiens
Synonyms:XLOC_013014
Chromosome:19
Strand:+
Coordinate:
Start Site(bp):22532626End Site(bp):22533494
Gene Summary:N/A
External Links:
Ensembl ID:ENSG00000269364
HGNC ID:HGNC:49756
Entrez Gene:100128139
VEGA ID:OTTHUMG00000182980
UCSC ID:N/A
ENA:DB454962
RefSeq Accession:NR_110663
UniProtKB:N/A

 

Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ZNF98
19
22391019
22532485
-
miRNA targets:N/A
Display:

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:3748C562729
Disease Name:esophagus squamous cell carcinomaEsophageal Squamous Cell Carcinoma
Category:Disease OntologyMeSH
Type:disease of cellular proliferationSupplementary Concept
Define:An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.A carcinoma that originates from cells on the surface of the middle and lower third of the ESOPHAGUS. Tumor cells exhibit typical squamous morphology and form large POLYPLOID lesions. Somatic mutations have been identified in RNF6, LZTS1, TGFBR2, DEC1, and WWOX1 genes.
Alias:SCC of esophagus//squamous cell carcinoma of esophagus (disorder)N/A

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:Microarray
Prediction Method:N/A

 

Reference

[1] PubMed ID:24522499
Disease Name:esophagus squamous cell carcinoma
Sample:N/A
Dysfunction Pattern:Expression
Validated Method:qRT-PCR//Microarray
Description:The three-lncRNA signature is a new biomarker for the prognosis of patients with OSCC, enabling more accurate prediction of survival
Author:Li J,Chen Z,Tian L,Zhou C,He MY,Gao Y,Wang S,Zhou F,Shi S,Feng X,Sun N,Liu Z,Skogerboe G,Dong J,Yao R,Zhao Y,Sun J,Zhang B,Yu Y,Shi X,Luo M,Shao K,Li N,Qiu B,Tan F,Chen R,He J
Year:2014
Title:LncRNA profile study reveals a three-lncRNA signature associated with the survival of patients with oesophageal squamous cell carcinoma.
Causality:No