Entry Detail



General Information

Database ID:LDA0004324
Species:Homo sapiens
Confidence Score:0.5483
Contents:>> ncRNA Information
>> Regulatory Relationship
>> Disease Information
>> Evidence Support
>> Reference

 

ncRNA Information

ncRNA Symbol:lincRNA-KCNK9-1
Full Name:N/A
Category:lncRNA
Species:Homo sapiens
Synonyms:N/A
Chromosome:N/A
Strand:N/A
Coordinate:
Start Site(bp):0End Site(bp):0
Gene Summary:N/A
External Links:
Ensembl ID:N/A
HGNC ID:N/A
Entrez Gene:N/A
VEGA ID:N/A
UCSC ID:N/A
ENA:N/A
RefSeq Accession:N/A
UniProtKB:N/A

 

Regulatory Relationship

mRNA targets:N/A
miRNA targets:N/A
Display:N/A

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:3068D005909
Disease Name:glioblastoma multiformeGlioblastoma
Category:Disease OntologyMeSH
Type:disease of cellular proliferationNeoplasms
Define:An astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derived_from multiple cell types including astrocytes and oligondroctyes.A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
Alias:adult glioblastoma multiforme//GBM//GBM (Glioblastoma)//grade IV adult Astrocytic tumor//primary glioblastoma multiforme//spongioblastoma multiformeGlioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

 

Evidence Support

Strong Evidence:N/A
Weak Evidence:Microarray
Prediction Method:N/A

 

Reference

[1] PubMed ID:25378224
Disease Name:Glioblastoma
Sample:brain
Dysfunction Pattern:Regulation [up-regulated]
Validated Method:Microarray
Description:A total of 84 lincRNAs which show a distinctive chromatin signature and a clear evolutionary conservation were filtered out based on John Rinn's paper (fold change >2 and p < 0.05). The top 10 up- and down-regulated lncRNAs were listed.
Author:Yan Y,Zhang L,Jiang Y,Xu T,Mei Q,Wang H,Qin R,Zou Y,Hu G,Chen J,Lu Y
Year:2015
Title:LncRNA and mRNA interaction study based on transcriptome profiles reveals potential core genes in the pathogenesis of human glioblastoma multiforme.
Causality:No