Entry Detail



General Information

Database ID:LDA0004362
Species:Homo sapiens
Confidence Score:0.8785
Contents:>> ncRNA Information
>> Regulatory Relationship
>> Disease Information
>> Evidence Support
>> Reference

 

ncRNA Information

ncRNA Symbol:uc059umi.1
Full Name:N/A
Category:lncRNA
Species:Homo sapiens
Synonyms:N/A
Chromosome:16
Strand:+
Coordinate:
Start Site(bp):56648880End Site(bp):56652636
Gene Summary:N/A
External Links:
Ensembl ID:N/A
HGNC ID:N/A
Entrez Gene:N/A
VEGA ID:N/A
UCSC ID:N/A
ENA:N/A
RefSeq Accession:N/A
UniProtKB:N/A

 

Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
MT4
16
56565049
56568957
+
MT3
16
56589074
56591088
+
MT2A
16
56608199
56609497
+
MT1E
16
56625475
56627112
+
MT1M
16
56632233
56633986
+
MT1A
16
56638666
56640087
+
MT1B
16
56651899
56653204
+
MT1F
16
56657694
56660698
+
MT1G
16
56666731
56668065
-
MT1H
16
56669814
56671129
+
AC026461.4
16
56676132
56677763
+
MT1X
16
56682424
56684196
+
NUP93
16
56730105
56850286
+
miRNA targets:N/A
Display:

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:3068D005909
Disease Name:glioblastoma multiformeGlioblastoma
Category:Disease OntologyMeSH
Type:disease of cellular proliferationNeoplasms
Define:An astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derived_from multiple cell types including astrocytes and oligondroctyes.A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
Alias:adult glioblastoma multiforme//GBM//GBM (Glioblastoma)//grade IV adult Astrocytic tumor//primary glioblastoma multiforme//spongioblastoma multiformeGlioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

 

Evidence Support

Strong Evidence:qPCR
Weak Evidence:Microarray
Prediction Method:N/A

 

Reference

[1] PubMed ID:25378224
Disease Name:Glioblastoma
Sample:brain
Dysfunction Pattern:Regulation [up-regulated]
Validated Method:qPCR//Microarray
Description:The detection of the expression level of selected six lncRNAs (ENST00000411660,NR_026664,HIT000337391,ENST00000451515,NR_015392,and uc002cds.2) by qPCR showed a good consistency with the microarray results.
Author:Yan Y,Zhang L,Jiang Y,Xu T,Mei Q,Wang H,Qin R,Zou Y,Hu G,Chen J,Lu Y
Year:2015
Title:LncRNA and mRNA interaction study based on transcriptome profiles reveals potential core genes in the pathogenesis of human glioblastoma multiforme.
Causality:No