Entry Detail



General Information

Database ID:LDA0004368
Species:Homo sapiens
Confidence Score:0.7311
Contents:>> ncRNA Information
>> Regulatory Relationship
>> Disease Information
>> Evidence Support
>> Reference

 

ncRNA Information

ncRNA Symbol:CCND2-AS1
Full Name:CCND2 antisense RNA 1
Category:lncRNA
Species:Homo sapiens
Synonyms:N/A
Chromosome:12
Strand:-
Coordinate:
Start Site(bp):4248765End Site(bp):4276184
Gene Summary:N/A
External Links:
Ensembl ID:ENSG00000256164
HGNC ID:HGNC:49398
Entrez Gene:103752584
VEGA ID:OTTHUMG00000168157
UCSC ID:N/A
ENA:BG413373
RefSeq Accession:NR_125790
UniProtKB:N/A

 

Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CCND2
12
4273772
4305350
+
TIGAR
12
4307763
4354593
+
FGF23
12
4368227
4379728
-
miRNA targets:N/A
Display:

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:3070D005910
Disease Name:malignant gliomaGlioma
Category:Disease OntologyMeSH
Type:disease of cellular proliferationNeoplasms
Define:A cell type cancer that has_material_basis_in glial cells and is located_in brain or located_in spine.Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
Alias:glial cell tumor//glioma//glioma (morphologic abnormality)//glioma NOS//glioma NOS (morphologic abnormality)//glioma, malignant//glioma, malignant, no ICD-O subtype//glioma, NOS//Gliomas (morphologic abnormality)//malignant glioma (morphologic abnormality)//malignant glioma - category//malignant Neuroglial tumor//Neuroglial tumorGliomas//Glial Cell Tumors//Glial Cell Tumor//Tumor, Glial Cell//Tumors, Glial Cell//Mixed Glioma//Glioma, Mixed//Gliomas, Mixed//Mixed Gliomas//Malignant Glioma//Glioma, Malignant//Gliomas, Malignant//Malignant Gliomas

 

Evidence Support

Strong Evidence:qPCR
Weak Evidence:N/A
Prediction Method:N/A

 

Reference

[1] PubMed ID:27923660
Disease Name:Glioma
Sample:glioma tissues and cell lines
Dysfunction Pattern:Expression [high expression]
Validated Method:qPCR
Description:Highly expressed lncRNA CCND2-AS1 promotes glioma cell proliferation through Wnt/β-catenin signaling.
Author:Zhang H,Wei DL,Wan L,Yan SF,Sun YH
Year:2017
Title:Highly expressed lncRNA CCND2-AS1 promotes glioma cell proliferation through Wnt/β-catenin signaling.
Causality:Yes