Entry Detail



General Information

Database ID:LDA0005883
Species:Homo sapiens
Confidence Score:0.7311
Contents:>> ncRNA Information
>> Regulatory Relationship
>> Disease Information
>> Evidence Support
>> Reference

 

ncRNA Information

ncRNA Symbol:intronic lncrna in tnk2 locus(ck327106)
Full Name:N/A
Category:lncRNA
Species:Homo sapiens
Synonyms:N/A
Chromosome:N/A
Strand:N/A
Coordinate:
Start Site(bp):0End Site(bp):0
Gene Summary:N/A
External Links:
Ensembl ID:N/A
HGNC ID:N/A
Entrez Gene:N/A
VEGA ID:N/A
UCSC ID:N/A
ENA:N/A
RefSeq Accession:N/A
UniProtKB:N/A

 

Regulatory Relationship

mRNA targets:N/A
miRNA targets:N/A
Display:N/A

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:1793D010190
Disease Name:pancreatic cancerPancreatic Neoplasms
Category:Disease OntologyMeSH
Type:disease of cellular proliferationNeoplasms//Digestive System Diseases//Endocrine System Diseases
Define:An endocrine gland cancer located_in the pancreas.Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Alias:Ca body of pancreas//Ca head of pancreas//Ca tail of pancreas//malignant neoplasm of body of pancreas//malignant neoplasm of head of pancreas//malignant neoplasm of tail of pancreas//pancreas neoplasm//pancreatic neoplasm//pancreatic tumorNeoplasm, Pancreatic//Pancreatic Neoplasm//Pancreas Neoplasms//Neoplasm, Pancreas//Neoplasms, Pancreas//Pancreas Neoplasm//Neoplasms, Pancreatic//Cancer of Pancreas//Pancreas Cancers//Pancreas Cancer//Cancer, Pancreas//Cancers, Pancreas//Pancreatic Cancer//Cancer, Pancreatic//Cancers, Pancreatic//Pancreatic Cancers//Cancer of the Pancreas

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:N/A
Prediction Method:N/A

 

Reference

[1] PubMed ID:22078386
Disease Name:pancreatic cancer
Sample:pancreatic tissue
Dysfunction Pattern:Regulation [down-regulated]
Validated Method:qRT-PCR
Description:Identification of genes specifically deregulated in malignant pancreatic epithelial cells is frequently confounded by an augmented stromal component in the latter due to the presence of proliferating stromal cells and infiltrating inflammatory cells. This expression signature comprised 104 protein-coding mRNAs and 43 lncRNAs,being 34 intronic and 9 intergenic transcripts in the primary pancreatic adenocarcinoma.
Author:Tahira AC,Kubrusly MS,Faria MF,Dazzani B,Fonseca RS,Maracaja-Coutinho V,Verjovski-Almeida S,Machado MC,Reis EM
Year:2011
Title:Long noncoding intronic RNAs are differentially expressed in primary and metastatic pancreatic cancer.
Causality:No

[2] PubMed ID:22078386
Disease Name:pancreatic cancer
Sample:pancreatic tissue
Dysfunction Pattern:Regulation [up-regulated]
Validated Method:qRT-PCR
Description:Sets of intronic lncRNAs expressed in pancreatic tissues whose abundance is correlated to PDAC or metastasis,thus pointing to the potential relevance of this class of transcripts in biological processes related to malignant transformation and metastasis in pancreatic cancer.
Author:Tahira AC,Kubrusly MS,Faria MF,Dazzani B,Fonseca RS,Maracaja-Coutinho V,Verjovski-Almeida S,Machado MC,Reis EM
Year:2011
Title:Long noncoding intronic RNAs are differentially expressed in primary and metastatic pancreatic cancer.
Causality:No