Entry Detail



General Information

Database ID:LDA0005930
Species:Homo sapiens
Confidence Score:0.8785
Contents:>> ncRNA Information
>> Regulatory Relationship
>> Disease Information
>> Evidence Support
>> Reference

 

ncRNA Information

ncRNA Symbol:LINC00491
Full Name:long intergenic non-protein coding RNA 491
Category:lncRNA
Species:Homo sapiens
Synonyms:BC008363
Chromosome:5
Strand:-
Coordinate:
Start Site(bp):102609156End Site(bp):102671559
Gene Summary:N/A
External Links:
Ensembl ID:ENSG00000250682
HGNC ID:HGNC:43428
Entrez Gene:285708
VEGA ID:OTTHUMG00000162775
UCSC ID:uc032vev.2
ENA:CN270888
RefSeq Accession:NR_103753
UniProtKB:N/A

 

Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
PAM
5
102753981
103031105
+
miRNA targets:N/A
Display:

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:3498N/A
Disease Name:pancreatic ductal adenocarcinomaN/A
Category:Disease OntologyN/A
Type:disease of cellular proliferationN/A
Define:A pancreatic adenocarcinoma that derives_from pancreatic duct cells.N/A
Alias:ductal adenocarcinoma of the pancreasN/A

 

Evidence Support

Strong Evidence:qPCR
Weak Evidence:Microarray
Prediction Method:N/A

 

Reference

[1] PubMed ID:25200694
Disease Name:pancreatic ductal adenocarcinoma
Sample:PDAC tissue
Dysfunction Pattern:Regulation [down-regulated]
Validated Method:qPCR//Microarray
Description:We found that the expression level of lncRNA BC008363 was significantly lower (23-fold) in PDAC tissues compared to corresponding nontumor pancreatic tissues,and patients with high levels of lncRNA BC008363 expression had significantly better survival rates than those with low levels of lncRNA BC008363 expression. lncRNA BC008363 may be a novel biomarker for the prognosis of pancreatic cancer.
Author:Li J,Liu D,Hua R,Zhang J,Liu W,Huo Y,Cheng Y,Hong J,Sun Y
Year:2014
Title:Long non-coding RNAs expressed in pancreatic ductal adenocarcinoma and lncRNA BC008363 an independent prognostic factor in PDAC.
Causality:No