Entry Detail



General Information

Database ID:LDA0006830
Species:Mus musculus
Confidence Score:0.7311
Contents:>> ncRNA Information
>> Regulatory Relationship
>> Disease Information
>> Evidence Support
>> Reference

 

ncRNA Information

ncRNA Symbol:VL30 RNAs
Full Name:N/A
Category:lncRNA
Species:Mus musculus
Synonyms:N/A
Chromosome:N/A
Strand:N/A
Coordinate:
Start Site(bp):0End Site(bp):0
Gene Summary:N/A
External Links:
Ensembl ID:N/A
HGNC ID:N/A
Entrez Gene:N/A
VEGA ID:N/A
UCSC ID:N/A
ENA:N/A
RefSeq Accession:N/A
UniProtKB:N/A

 

Regulatory Relationship

mRNA targets:N/A
miRNA targets:N/A
Display:N/A

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:1909D008545
Disease Name:melanomaMelanoma
Category:Disease OntologyMeSH
Type:disease of cellular proliferationNeoplasms
Define:A cell type cancer that has_material_basis_in abnormally proliferating cells derived_from melanocytes which are found in skin, the bowel and the eye.A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
Alias:malignant melanoma//NaevocarcinomaMelanomas//Malignant Melanoma//Malignant Melanomas//Melanoma, Malignant//Melanomas, Malignant

 

Evidence Support

Strong Evidence:Southern blot
Weak Evidence:N/A
Prediction Method:N/A

 

Reference

[1] PubMed ID:11959915
Disease Name:melanoma
Sample:melanoma cell line
Dysfunction Pattern:N/A
Validated Method:Southern blot
Description:Infection of a human melanoma cell line by a retroviral vector resulted in transmission of a mouse vl30 (mvl30-1) retroelement rna to some of the cells infected by the retrovirus,The metastatic effect might be mediated directly by a noncoding mvl30-1 rna or by a peptide or small protein encoded by one of the short orfs in the mvl30-1 rna.
Author:Song X,Wang B,Bromberg M,Hu Z,Konigsberg W,Garen A
Year:2002
Title:Retroviral-mediated transmission of a mouse VL30 RNA to human melanoma cells promotes metastasis in an immunodeficient mouse model.
Causality:No