Entry Detail



General Information

Database ID:LDA0006840
Species:Mus musculus
Confidence Score:0.8808
Contents:>> ncRNA Information
>> Regulatory Relationship
>> Disease Information
>> Evidence Support
>> Reference

 

ncRNA Information

ncRNA Symbol:Mirt2
Full Name:myocardial infraction associated transcript 2
Category:lncRNA
Species:Mus musculus
Synonyms:Gm10872//Gm24562
Chromosome:15
Strand:-
Coordinate:
Start Site(bp):76267135End Site(bp):76267419
Gene Summary:N/A
External Links:
Ensembl ID:ENSMUSG00000092920
HGNC ID:N/A
Entrez Gene:100038659
VEGA ID:N/A
UCSC ID:N/A
ENA:N/A
RefSeq Accession:N/A
UniProtKB:Q3U256

 

Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
Plec
15
76170974
76232574
-
Parp10
15
76231174
76243441
-
Grina
15
76246764
76249904
+
Spatc1
15
76268089
76292572
+
Smpd5
15
76294348
76296896
+
Oplah
15
76296601
76328015
-
Exosc4
15
76327397
76330677
+
Gpaa1
15
76331231
76334907
+
Cyc1
15
76343523
76346260
+
Sharpin
15
76347040
76351111
-
Maf1
15
76351294
76354380
+
Gm35339
15
76354432
76365201
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
Mir1942
15
76215611
76215673
-
Mir6953
15
76248191
76248258
+
Mir3079
15
76290879
76290968
-
Display:

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:5844D009203
Disease Name:myocardial infarctionMyocardial Infarction
Category:Disease OntologyMeSH
Type:disease of anatomical entityCardiovascular Diseases
Define:A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
Alias:heart attack//Myocardial infarctInfarction, Myocardial//Infarctions, Myocardial//Myocardial Infarctions//Cardiovascular Stroke//Cardiovascular Strokes//Stroke, Cardiovascular//Strokes, Cardiovascular//Heart Attack//Heart Attacks//Myocardial Infarct//Infarct, Myocardial//Infarcts, Myocardial//Myocardial Infarcts

 

Evidence Support

Strong Evidence:ISH//qPCR
Weak Evidence:N/A
Prediction Method:N/A

 

Reference

[1] PubMed ID:24917243
Disease Name:myocardial infarction
Sample:N/A
Dysfunction Pattern:Regulation [up-regulated]
Validated Method:ISH//qPCR
Description:Among these, 2 lncRNAs, called myocardial infarction-associated transcript 1 (MIRT1) and 2 (MIRT2), showed robust up-regulation in the MI group: 5-fold and 13-fold, respectively. Up-regulation of these 2 lncRNAs after MI was confirmed by quantitative PCR in an independent validation group of 8 MI and 8 sham-operated mice(9-fold and 16-fold for MIRT1 and MIRT2,P<0.001).
Author:Zangrando J,Zhang L,Vausort M,Maskali F,Marie PY,Wagner DR,Devaux Y
Year:2014
Title:Identification of candidate long non-coding RNAs in response to myocardial infarction.
Causality:No