Entry Detail



General Information

Database ID:LDA0006917
Species:Mus musculus
Confidence Score:0.7311
Contents:>> ncRNA Information
>> Regulatory Relationship
>> Disease Information
>> Evidence Support
>> Reference

 

ncRNA Information

ncRNA Symbol:H19
Full Name:H19, imprinted maternally expressed transcript
Category:lncRNA
Species:Mus musculus
Synonyms:N/A
Chromosome:7
Strand:-
Coordinate:
Start Site(bp):142575529End Site(bp):142578143
Gene Summary:N/A
External Links:
Ensembl ID:ENSMUSG00000000031
HGNC ID:N/A
Entrez Gene:14955
VEGA ID:OTTMUSG00000014998
UCSC ID:N/A
ENA:N/A
RefSeq Accession:N/A
UniProtKB:Q61639

 

Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
Lsp1
7
142460809
142494867
+
Tnnt3
7
142498836
142516009
+
Mrpl23
7
142532686
142540747
+
Igf2
7
142650766
142666816
-
AC013548.1
7
142650769
142669942
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
Mir675
7
142577064
142577147
-
Mir483
7
142654924
142654996
-
Display:

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:10283D011471
Disease Name:prostate cancerProstatic Neoplasms
Category:Disease OntologyMeSH
Type:disease of cellular proliferationNeoplasms//Male Urogenital Diseases
Define:A male reproductive organ cancer that is located_in the prostate.Tumors or cancer of the PROSTATE.
Alias:hereditary prostate cancer//malignant tumor of the prostate//NGP - new growth of prostate//prostate cancer, familial//prostate neoplasm//prostatic cancer//prostatic neoplasm//tumor of the prostateProstate Neoplasms//Neoplasms, Prostate//Neoplasm, Prostate//Prostate Neoplasm//Neoplasms, Prostatic//Neoplasm, Prostatic//Prostatic Neoplasm//Prostate Cancer//Cancer, Prostate//Cancers, Prostate//Prostate Cancers//Cancer of the Prostate//Prostatic Cancer//Cancer, Prostatic//Cancers, Prostatic//Prostatic Cancers//Cancer of Prostate

 

Evidence Support

Strong Evidence:ChIP
Weak Evidence:N/A
Prediction Method:N/A

 

Reference

[1] PubMed ID:18459101
Disease Name:prostate cancer
Sample:prostate cancer tissue
Dysfunction Pattern:Regulation [up-regulated]
Validated Method:ChIP
Description:A significant increase in both igf2 and h19 expression was found in choline and methionine deficient prostate tissues compared to controls.
Author:Dobosy JR,Fu VX,Desotelle JA,Srinivasan R,Kenowski ML,Almassi N,Weindruch R,Svaren J,Jarrard DF
Year:2008
Title:A methyl-deficient diet modifies histone methylation and alters Igf2 and H19 repression in the prostate.
Causality:No