Entry Detail



General Information

Database ID:LDA0007023
Species:Rattus norvegicus
Confidence Score:0.9087
Contents:>> ncRNA Information
>> Regulatory Relationship
>> Disease Information
>> Evidence Support
>> Reference

 

ncRNA Information

ncRNA Symbol:Asb3
Full Name:ankyrin repeat and SOCS box-containing 3
Category:lncRNA
Species:Rattus norvegicus
Synonyms:N/A
Chromosome:14
Strand:+
Coordinate:
Start Site(bp):115391609End Site(bp):115446152
Gene Summary:INVOLVED IN intracellular signal transduction (inferred); protein ubiquitination (inferred); INTERACTS WITH bisphenol A; flutamide; vinclozolin
External Links:
Ensembl ID:ENSRNOG00000032471
HGNC ID:N/A
Entrez Gene:364227
VEGA ID:N/A
UCSC ID:N/A
ENA:N/A
RefSeq Accession:N/A
UniProtKB:N/A

 

Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
Erlec1
14
115314890
115352562
-
Chac2
14
115383910
115391652
-
miRNA targets:N/A
Display:

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:1287D002318
Disease Name:cardiovascular system diseaseCardiovascular Diseases
Category:Disease OntologyMeSH
Type:disease of anatomical entityCardiovascular Diseases
Define:A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
Alias:disease of subdivision of hemolymphoid systemCardiovascular Disease//Disease, Cardiovascular//Diseases, Cardiovascular

 

Evidence Support

Strong Evidence:Immunoblot
Weak Evidence:Microarray//Sequencing
Prediction Method:N/A

 

Reference

[1] PubMed ID:25385761
Disease Name:cardiovascular system disease
Sample:N/A
Dysfunction Pattern:N/A
Validated Method:Immunoblot//Microarray//Sequencing
Description:The protein expression status of 4 target genes,Asb3,Chac2,Pex11b,and Sp5,were differentially expressed between the relevant strain comparisons,thereby suggesting that the differentially expressed lncRNAs associated with these genes are candidate genetic determinants of blood pressure
Author:Gopalakrishnan K,Kumarasamy S,Mell B,Joe B
Year:2015
Title:Genome-wide identification of long noncoding RNAs in rat models of cardiovascular and renal disease.
Causality:No