Entry Detail



General Information

Database ID:LDA0007045
Species:Rattus norvegicus
Confidence Score:0.5483
Contents:>> ncRNA Information
>> Regulatory Relationship
>> Disease Information
>> Evidence Support
>> Reference

 

ncRNA Information

ncRNA Symbol:MRAK040488
Full Name:N/A
Category:lncRNA
Species:Rattus norvegicus
Synonyms:N/A
Chromosome:N/A
Strand:N/A
Coordinate:
Start Site(bp):0End Site(bp):0
Gene Summary:N/A
External Links:
Ensembl ID:N/A
HGNC ID:N/A
Entrez Gene:N/A
VEGA ID:N/A
UCSC ID:N/A
ENA:N/A
RefSeq Accession:N/A
UniProtKB:N/A

 

Regulatory Relationship

mRNA targets:N/A
miRNA targets:N/A
Display:N/A

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:3525D020244
Disease Name:middle cerebral artery infarctionInfarction, Middle Cerebral Artery
Category:Disease OntologyMeSH
Type:disease of anatomical entityNervous System Diseases//Cardiovascular Diseases
Define:N/ANECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
Alias:N/AMiddle Cerebral Artery Circulation Infarction//Middle Cerebral Artery Infarction//Cerebral Infarction, Middle Cerebral Artery//Stroke, Middle Cerebral Artery//MCA Infarction//Middle Cerebral Artery Stroke//Left Middle Cerebral Artery Infarction//Middle Cerebral Artery Embolus//Embolus, Middle Cerebral Artery//Middle Cerebral Artery Occlusion//Occlusion, Middle Cerebral Artery//Thrombotic Infarction, Middle Cerebral Artery//Middle Cerebral Artery Thrombotic Infarction//Middle Cerebral Artery Thrombosis//Thrombosis, Middle Cerebral Artery//Right Middle Cerebral Artery Infarction//Embolic Infarction, Middle Cerebral Artery//Middle Cerebral Artery Embolic Infarction//Middle Cerebral Artery Syndrome

 

Evidence Support

Strong Evidence:N/A
Weak Evidence:Microarray
Prediction Method:N/A

 

Reference

[1] PubMed ID:22949471
Disease Name:middle cerebral artery infarction
Sample:brain
Dysfunction Pattern:Regulation [down-regulated]
Validated Method:Microarray
Description:Three hundred fifty-nine lncRNAs were upregulated (>2-fold) and 84 were downregulated (<0.5-fold) at 3 hours to 12 hours of reperfusion after middle cerebral artery occlusion compared with sham. Sixty-two stroke-responsive lncRNAs showed >90% sequence homology with exons of protein-coding genes. Promoters of stroke-responsive lncRNA genes and their homologous protein-coding genes showed highly overlapping transcription factor binding sites.
Author:Dharap A,Nakka VP,Vemuganti R
Year:2012
Title:Effect of focal ischemia on long noncoding RNAs.
Causality:No