Entry Detail



General Information

Database ID:LDA0007386
Species:Homo sapiens
Confidence Score:0.9074
Contents:>> ncRNA Information
>> Regulatory Relationship
>> Disease Information
>> Evidence Support
>> Reference

 

ncRNA Information

ncRNA Symbol:MIR100HG
Full Name:mir-100-let-7a-2-mir-125b-1 cluster host gene
Category:lncRNA
Species:Homo sapiens
Synonyms:AGD1//lncRNA-N2
Chromosome:11
Strand:-
Coordinate:
Start Site(bp):122028327End Site(bp):122556721
Gene Summary:This gene produces long non-coding RNAs that act as regulators of cell proliferation. Alternative promoter usage and splicing results in multiple transcript variants. Some transcript variants may promote growth, while others may act to negatively regulate cell division. [provided by RefSeq, May 2016]
External Links:
Ensembl ID:ENSG00000255248
HGNC ID:HGNC:39522
Entrez Gene:399959
VEGA ID:OTTHUMG00000166035
UCSC ID:uc009zbb.2
ENA:AK091713
RefSeq Accession:NR_024430
UniProtKB:N/A

 

Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
BLID
11
122115354
122116215
-
UBASH3B
11
122655675
122814473
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
MIR125B1
11
122099757
122099844
-
MIRLET7A2
11
122146522
122146593
-
MIR100
11
122152229
122152308
-
Display:

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:4362D002583
Disease Name:cervical cancerUterine Cervical Neoplasms
Category:Disease OntologyMeSH
Type:disease of cellular proliferationNeoplasms//Female Urogenital Diseases and Pregnancy Complications
Define:A female reproductive organ cancer that is located_in the cervix.Tumors or cancer of the UTERINE CERVIX.
Alias:cervical neoplasm//cervix cancer//cervix uteri cancer//neoplasm of uterine cervix (disorder)//tumor of the Cervix Uteri//uterine cervical neoplasmCervical Neoplasm, Uterine//Cervical Neoplasms, Uterine//Neoplasm, Uterine Cervical//Neoplasms, Uterine Cervical//Uterine Cervical Neoplasm//Neoplasms, Cervical//Cervical Neoplasms//Cervical Neoplasm//Neoplasm, Cervical//Neoplasms, Cervix//Cervix Neoplasms//Cervix Neoplasm//Neoplasm, Cervix//Cancer of the Uterine Cervix//Cancer of the Cervix//Cervical Cancer//Uterine Cervical Cancer//Cancer, Uterine Cervical//Cancers, Uterine Cervical//Cervical Cancer, Uterine//Cervical Cancers, Uterine//Uterine Cervical Cancers//Cancer of Cervix//Cervix Cancer//Cancer, Cervix//Cancers, Cervix

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:Bioinformatic analysis
Prediction Method:LRLSLDA-LNCSIM1//LRLSLDA-LNCSIM2//TAM

 

Reference

[1] PubMed ID:27035672
Disease Name:cervical cancer
Sample:N/A
Dysfunction Pattern:Expression
Validated Method:qRT-PCR//Bioinformatic analysis
Description:MIR100HG and AC024560.2 may be a potential biomarkers of PLNM and these lncRNAs may provide broader perspective for combating cervical cancer metastasis.
Author:Shang C,Zhu W,Liu T,Wang W,Huang G,Huang J,Zhao P,Zhao Y,Yao S
Year:2016
Title:Characterization of long non-coding RNA expression profiles in lymph node metastasis of early-stage cervical cancer.
Causality:No