Entry Detail



General Information

Database ID:LDA0007474
Species:Homo sapiens
Confidence Score:0.956
Contents:>> ncRNA Information
>> Regulatory Relationship
>> Disease Information
>> Evidence Support
>> Reference

 

ncRNA Information

ncRNA Symbol:ZNF582-AS1
Full Name:ZNF582 antisense RNA 1 (head to head)
Category:lncRNA
Species:Homo sapiens
Synonyms:N/A
Chromosome:19
Strand:+
Coordinate:
Start Site(bp):56393656End Site(bp):56399172
Gene Summary:N/A
External Links:
Ensembl ID:ENSG00000267454
HGNC ID:HGNC:25213
Entrez Gene:386758
VEGA ID:OTTHUMG00000182151
UCSC ID:uc002qnb.3
ENA:AW160702//BC036928
RefSeq Accession:NR_037159
UniProtKB:N/A

 

Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ZSCAN5A
19
56219670
56368383
-
EDDM13
19
56272769
56310450
+
ZNF582
19
56375846
56393545
-
ZNF583
19
56397966
56436035
+
ZNF667
19
56439325
56478065
-
miRNA targets:N/A
Display:

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:9256D015179
Disease Name:colorectal cancerColorectal Neoplasms
Category:Disease OntologyMeSH
Type:disease of cellular proliferationNeoplasms//Digestive System Diseases
Define:A large intestine cancer that is located_in the colon and/or located_in the rectum.Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
Alias:N/ANeoplasms, Colorectal//Colorectal Neoplasm//Neoplasm, Colorectal//Colorectal Tumors//Colorectal Tumor//Tumor, Colorectal//Tumors, Colorectal//Colorectal Carcinoma//Carcinoma, Colorectal//Carcinomas, Colorectal//Colorectal Carcinomas//Colorectal Cancer//Cancer, Colorectal//Cancers, Colorectal//Colorectal Cancers

 

Evidence Support

Strong Evidence:ChIP//qRT-PCR
Weak Evidence:Microarray
Prediction Method:LDAP

 

Reference

[1] PubMed ID:27215978
Disease Name:colorectal cancer
Sample:N/A
Dysfunction Pattern:Regulation
Validated Method:ChIP//qRT-PCR//Microarray
Description:ZNF582-AS1 may be a novel tumor-suppressive lncRNA.
Author:Kumegawa K,Maruyama R,Yamamoto E,Ashida M,Kitajima H,Tsuyada A,Niinuma T,Kai M,Yamano HO,Sugai T,Tokino T,Shinomura Y,Imai K,Suzuki H
Year:2016
Title:A genomic screen for long noncoding RNA genes epigenetically silenced by aberrant DNA methylation in colorectal cancer.
Causality:No