Entry Detail

General Information

Database ID: LDA0000670
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Yes

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:FOXP4-AS1
Full Name:FOXP4 antisense RNA 1
Category:LncRNA
Species:Homo sapiens
Synonyms:-
Chromosome:6
Strand:-
Coordinate:
Start Site(bp):41523895End Site(bp):41548621
External Links:
Ensembl ID:ENSG00000234753
Ensembl Transcript ID:N/A
Entrez Gene:101060264.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:20   
More Information
Causal Disease Number:16
Network:
Top Causal Diseases:
Carcinoma, Hepatocellular  (Score: 0.999893)
Carcinoma, Hepatocellular  (Score: 0.999893)
Esophageal Squamous Cell Carcinoma  (Score: 0.731059)
Colorectal Neoplasms  (Score: 0.731059)
Thyroid Cancer, Papillary  (Score: 0.731059)
Uterine Cervical Neoplasms  (Score: 0.731059)
Prostatic Neoplasms  (Score: 0.731059)
Lymphoma, Mantle-Cell  (Score: 0.731059)
Sarcoma, Ewing  (Score: 0.731059)
Esophageal Squamous Cell Carcinoma  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:3369D012512
Disease Name:Ewing sarcomaSarcoma, Ewing
Category:Disease OntologyMeSH
Type:Neoplasms
Define:A connective tissue cancer that has_material_basis_in neural crest cells derives_from undeveloped, undifferentiated neuroectoderm.A malignant tumor of the bone which always arises in the medullary tissue, occurring more often in cylindrical bones. The tumor occurs usually before the age of 20, about twice as frequently in males as in females.
Alias:Ewing's family localized tumor//Ewing's sarcoma/peripheral primitive neuroectodermal tumor//Ewing's tumor//Ewings sarcoma//Ewings sarcoma-primitive neuroectodermal tumor//PNET of Thoracopulmonary Region//localized Ewing sarcoma//localized Ewing's sarcoma//localized Ewing's sarcoma/peripheral primitive neuroectodermal tumor//localized Ewing's tumor//localized peripheral primitive neuroectodermal tumor//peripheral primitive neuroectodermal tumorSarcoma, Ewing//Sarcoma, Ewing's//Sarcoma, Ewings//Ewing's Sarcoma//Ewings Sarcoma//Ewing's Tumor//Ewings Tumor//Tumor, Ewing's//Ewing Sarcoma//Ewing Tumor//Tumor, Ewing

 

Disease Association Statistics

Total Associated ncRNA Number:8   
More Information
Causal ncRNA Number:4
Network:
Top Causal ncRNAs:
FOXP4-AS1  (Score: 0.731059)
TUG1  (Score: 0.731059)
FOXP4-AS1  (Score: 0.731059)
TUG1  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:Western Blot//Migration Assay//qRT-PCR//Cell Proliferation Assay//Invasion Assay
Weak Evidence:

 

Reference

[1] PubMed ID:34765540
Disease Name:Sarcoma, Ewing
Sample:ES tissues
Dysfunction Pattern:Expression(highly expressed)
Validated Method:Western Blot//Migration Assay//qRT-PCR//Cell Proliferation Assay//Invasion Assay
Description:Herein, we established that FOXP4-AS1 was up-regulated in ES and this correlated with poor prognosis.
Causality:Yes
Causal Description:On the contrary, up-regulation of FOXP4-AS1 promoted the growth, migration, as well as invasion of ES.
Clinical-realted Application:Herein, we established that FOXP4-AS1 was up-regulated in ES and this correlated with poor prognosis.