Entry Detail

General Information

Database ID: LDA0001816
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:LINC00886
Full Name:long intergenic non-protein coding RNA 886
Category:LncRNA
Species:Homo sapiens
Synonyms:-
Chromosome:3
Strand:-
Coordinate:
Start Site(bp):156747343End Site(bp):156817062
External Links:
Ensembl ID:ENSG00000240875
Ensembl Transcript ID:N/A
Entrez Gene:730091.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:2   
More Information
Causal Disease Number:2
Network:
Top Causal Diseases:
laryngeal carcinoma  (Score: 0.731059)
laryngeal carcinoma  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:2600
Disease Name:laryngeal carcinoma
Category:Disease Ontology
Type:Neoplasms
Define:A larynx cancer that has_material_basis_in epithelial cells.
Alias:cancer of larynx//carcinoma of larynx

 

Disease Association Statistics

Total Associated ncRNA Number:22   
More Information
Causal ncRNA Number:18
Network:
Top Causal ncRNAs:
FOXD2-AS1  (Score: 0.731059)
WTAPP1  (Score: 0.731059)
SNHG3  (Score: 0.731059)
circABCB10  (Score: 0.731059)
CASC9  (Score: 0.731059)
AFAP1-AS1  (Score: 0.731059)
LINC01303  (Score: 0.731059)
LINC00886  (Score: 0.731059)
MALAT1  (Score: 0.731059)
FOXD2-AS1  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR//Western Blot
Weak Evidence:

 

Reference

[1] PubMed ID:32111441
Disease Name:laryngeal carcinoma
Sample:tumor tissues and laryngeal cancer cell lines
Dysfunction Pattern:Expression[lower expressed]
Validated Method:qRT-PCR//Western Blot
Description:The remarkable downregulation of LINC00886 was observed in tumor tissues and laryngeal cancer cell lines.
Causality:Yes
Causal Description: Over-expression of LINC00886 dramatically mitigated cell proliferation, migration, and invasion in vitro as well as suppressed tumor growth in vivo.
Clinical-realted Application: