Entry Detail

General Information

Database ID: LDA0002051
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:LINC01555
Full Name:long intergenic non-protein coding RNA 1555
Category:LncRNA
Species:Homo sapiens
Synonyms:C1orf180
Chromosome:1
Strand:-
Coordinate:
Start Site(bp):84628230End Site(bp):84635020
External Links:
Ensembl ID:ENSG00000180869
Ensembl Transcript ID:N/A
Entrez Gene:439927.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:4   
More Information
Causal Disease Number:4
Network:
Top Causal Diseases:
Colorectal Neoplasms  (Score: 0.731059)
Small Cell Lung Carcinoma  (Score: 0.731059)
Colorectal Neoplasms  (Score: 0.731059)
Small Cell Lung Carcinoma  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:D055752
Disease Name:Small Cell Lung Carcinoma
Category:MeSH
Type:Neoplasms
Define:A form of highly malignant lung cancer that is composed of small ovoid cells (SMALL CELL CARCINOMA).
Alias:Small Cell Lung Carcinoma//Small Cell Lung Cancer//Oat Cell Lung Cancer//Small Cell Cancer Of The Lung//Carcinoma, Small Cell Lung//Oat Cell Carcinoma of Lung

 

Disease Association Statistics

Total Associated ncRNA Number:28   
More Information
Causal ncRNA Number:24
Network:
Top Causal ncRNAs:
circPVT1  (Score: 0.731059)
KCNQ1OT1  (Score: 0.731059)
LUADT1  (Score: 0.731059)
LINC01555  (Score: 0.731059)
LINC01116  (Score: 0.731059)
CASC11  (Score: 0.731059)
ZFPM2-AS1  (Score: 0.731059)
MCM3AP-AS1  (Score: 0.731059)
NEF  (Score: 0.731059)
HIF1A-AS2  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:RNA Pull-Down//Western Blot//Transfection//CCK8//qRT-PCR//Flow Cytometry//RIP//Luciferase Report Assay//Colony Formation Assay
Weak Evidence:

 

Reference

[1] PubMed ID:36045598
Disease Name:Small Cell Lung Carcinoma
Sample:SCLC tissues and cells
Dysfunction Pattern:Interaction(microRNA-122-5p/clic1 axis )
Validated Method:RNA Pull-Down//Western Blot//Transfection//CCK8//qRT-PCR//Flow Cytometry//RIP//Luciferase Report Assay//Colony Formation Assay
Description: Linc01555 was elevated in SCLC tissues and cells, and in H446/DDP cells or DMS-53/DDP vs. its parental cells; Restraining linc01555 or elevating miR-122-5p repressed the proliferation and metastasis of H446/DDP or DMS-53/DDP cells and vasculogenic mimicry (VM) formation. CLIC1 mediated miR-122-5p to influence the occurrence and development of SCLC. Linc01555 competitively combined with miR-122-5p, which targeted CLIC1.
Causality:Yes
Causal Description: Linc01555 was elevated in SCLC tissues and cells, and in H446/DDP cells or DMS-53/DDP vs. its parental cells; Restraining linc01555 or elevating miR-122-5p repressed the proliferation and metastasis of H446/DDP or DMS-53/DDP cells and vasculogenic mimicry (VM) formation.
Clinical-realted Application: