Entry Detail

General Information

Database ID: LDA0003658
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:CHST15
Full Name:carbohydrate sulfotransferase 15
Category:LncRNA
Species:Homo sapiens
Synonyms:BRAG|GALNAC4S-6ST
Chromosome:10
Strand:-
Coordinate:
Start Site(bp):124007668End Site(bp):124093598
External Links:
Ensembl ID:ENSG00000182022
Ensembl Transcript ID:N/A
Entrez Gene:51363.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:2   
More Information
Causal Disease Number:2
Network:
Top Causal Diseases:
Lung Neoplasms  (Score: 0.731059)
Lung Neoplasms  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:1324D008175
Disease Name:lung cancerLung Neoplasms
Category:Disease OntologyMeSH
Type:Neoplasms
Define:A respiratory system cancer that is located_in the lung.Tumors or cancer of the LUNG.
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung

 

Disease Association Statistics

Total Associated ncRNA Number:344   
More Information
Causal ncRNA Number:282
Network:
Top Causal ncRNAs:
OIP5-AS1  (Score: 0.999893)
OIP5-AS1  (Score: 0.999893)
MNX1-AS1  (Score: 0.999893)
NEAT1  (Score: 0.999893)
MNX1-AS1  (Score: 0.999893)
NEAT1  (Score: 0.999893)
circHIPK3  (Score: 0.985791)
GAS5  (Score: 0.985791)
PCAT1  (Score: 0.985791)
NNT-AS1  (Score: 0.985791)
More Information

 

Evidence Support

Strong Evidence:colony Formation Assay//RNA Pull-Down//Western Blot//Transfection//qPCR//Flow Cytometry//PCR//ELISA//Colony Formation Assay//IF
Weak Evidence:

 

Reference

[1] PubMed ID:33777742
Disease Name:Lung Neoplasms
Sample:lung cancer tissues and cell lines
Dysfunction Pattern:Interaction(miR-155-5p and miR-194-5p / PD-L1)
Validated Method:colony Formation Assay//RNA Pull-Down//Western Blot//Transfection//qPCR//Flow Cytometry//PCR//ELISA//Colony Formation Assay//Bioinformatics Analysis//IF
Description:CircCHST15 and PD-L1 were high-expressed in lung cancer, and the two was positively correlated. CircCHST15 targeted miR-155-5p and miR-194-5p, the later further targeted PD-L1.
Causality:Yes
Causal Description:Lung cancer cell viability and proliferation were increased by miR-155-5p and inhibited by miR-194-5p.
Clinical-realted Application: