Entry Detail

General Information

Database ID: LDA0003696
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:CYTOR
Full Name:cytoskeleton regulator RNA
Category:LncRNA
Species:Homo sapiens
Synonyms:C2orf59|LINC00152|NCRNA00152
Chromosome:2
Strand:+
Coordinate:
Start Site(bp):87455427End Site(bp):87521518
External Links:
Ensembl ID:ENSG00000222041
Ensembl Transcript ID:N/A
Entrez Gene:112597.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:52   
More Information
Causal Disease Number:46
Network:
Top Causal Diseases:
Stomach Neoplasms  (Score: 1)
Stomach Neoplasms  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Squamous Cell Carcinoma of Head and Neck  (Score: 1)
Squamous Cell Carcinoma of Head and Neck  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Breast Neoplasms  (Score: 0.999893)
Esophageal Squamous Cell Carcinoma  (Score: 0.999893)
Glioma  (Score: 0.999893)
Esophageal Squamous Cell Carcinoma  (Score: 0.999893)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:0050865
Disease Name:tongue squamous cell carcinoma
Category:Disease Ontology
Type:Neoplasms
Define:A head and neck squamous cell carcinoma that is located_in the tongue.
Alias:

 

Disease Association Statistics

Total Associated ncRNA Number:140   
More Information
Causal ncRNA Number:70
Network:
Top Causal ncRNAs:
hsa_circ_0001742  (Score: 1)
hsa_circ_0001742  (Score: 1)
MALAT1  (Score: 1)
MALAT1  (Score: 1)
CASC15  (Score: 0.985791)
hsa_circ_0002162  (Score: 0.985791)
CASC15  (Score: 0.985791)
hsa_circ_0000231  (Score: 0.985791)
hsa_circ_0002162  (Score: 0.985791)
hsa_circ_0000231  (Score: 0.985791)
More Information

 

Evidence Support

Strong Evidence:Western Blot//Flow Cytometry//qRT-PCR//Luciferase Report Assay//Cell Proliferation Assay//Transwell Assay
Weak Evidence:

 

Reference

[1] PubMed ID:32194700
Disease Name:tongue squamous cell carcinoma
Sample:TSCC tissues
Dysfunction Pattern:interaction[miRNA-193b-3p]
Validated Method:Western Blot//Flow Cytometry//qRT-PCR//Luciferase Report Assay//Cell Proliferation Assay//Transwell Assay
Description:The present study revealed that long intergenic non-coding RNA 00152 (LINC00152) expression was significantly increased in human TSCC tissues compared with in tissues from matched controls using RT-qPCR. Overall, the results of the present study suggested that increased LINC00152 expression in TSCC tissues may act as a sponge of miR-193b-3p to promote cancer progression in vitro.
Causality:Yes
Causal Description:In TSCC cell lines, CAL-27 and SCC-9, LINC00152 was revealed to promote TSCC cell proliferation, enhance cell cycle progression and inhibit cell apoptosis.
Clinical-realted Application: