Entry Detail

General Information

Database ID: LDA0003761
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:CCDC144NL-AS1
Full Name:CCDC144NL antisense RNA 1
Category:LncRNA
Species:Homo sapiens
Synonyms:-
Chromosome:17
Strand:+
Coordinate:
Start Site(bp):20868527End Site(bp):20930041
External Links:
Ensembl ID:ENSG00000233098
Ensembl Transcript ID:N/A
Entrez Gene:440416.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:14   
More Information
Causal Disease Number:12
Network:
Top Causal Diseases:
Stomach Neoplasms  (Score: 0.985791)
Stomach Neoplasms  (Score: 0.985791)
Carcinoma, Non-Small-Cell Lung  (Score: 0.731059)
Colorectal Neoplasms  (Score: 0.731059)
Carcinoma, Hepatocellular  (Score: 0.731059)
Squamous Cell Carcinoma of Head and Neck  (Score: 0.731059)
Endometriosis  (Score: 0.731059)
Carcinoma, Non-Small-Cell Lung  (Score: 0.731059)
Colorectal Neoplasms  (Score: 0.731059)
Carcinoma, Hepatocellular  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:289D004715
Disease Name:endometriosisEndometriosis
Category:Disease OntologyMeSH
Type:Urogenital Diseases
Define:A female reproductive system disease characterized by the growth of endometrial tissue outside the uterine body.A condition in which functional endometrial tissue is present outside the UTERUS. It is often confined to the PELVIS involving the OVARY, the ligaments, cul-de-sac, and the uterovesical peritoneum.
Alias:Endometriosis//Endometrioses//Endometrioma//Endometriomas

 

Disease Association Statistics

Total Associated ncRNA Number:46   
More Information
Causal ncRNA Number:42
Network:
Top Causal ncRNAs:
MALAT1  (Score: 0.999893)
AFAP1-AS1  (Score: 0.999893)
MALAT1  (Score: 0.999893)
AFAP1-AS1  (Score: 0.999893)
HOTAIR  (Score: 0.985791)
HOTAIR  (Score: 0.985791)
circATRNL1  (Score: 0.985791)
circATRNL1  (Score: 0.985791)
DHRS4  (Score: 0.731059)
CCDC144NL-AS1  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:30496345
Disease Name:Endometriosis
Sample:EC tissues
Dysfunction Pattern:Expression[highly expressed]
Validated Method:qRT-PCR
Description:CCDC144NL-AS1 expression was upregulated in EC tissues compared to EU and normal endometrial (NE) tissues.
Causality:Yes
Causal Description:CCDC144NL-AS1 depletion suppressed the migration and invasion of hEM15A cells, but exerted no effects on cell adhesion, proliferation, apoptosis, or cell cycle.
Clinical-realted Application: