Entry Detail

General Information

Database ID: LDA0004233
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:ANKRD40CL
Full Name:ANKRD40 C-terminal like
Category:LncRNA
Species:Homo sapiens
Synonyms:C17orf73|LINC00483
Chromosome:17
Strand:-
Coordinate:
Start Site(bp):50761030End Site(bp):50767518
External Links:
Ensembl ID:ENSG00000167117
Ensembl Transcript ID:N/A
Entrez Gene:55018.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:8   
More Information
Causal Disease Number:8
Network:
Top Causal Diseases:
Colorectal Neoplasms  (Score: 0.985791)
Colorectal Neoplasms  (Score: 0.985791)
Stomach Neoplasms  (Score: 0.731059)
pancreatic ductal adenocarcinoma  (Score: 0.731059)
Uterine Cervical Neoplasms  (Score: 0.731059)
Stomach Neoplasms  (Score: 0.731059)
pancreatic ductal adenocarcinoma  (Score: 0.731059)
Uterine Cervical Neoplasms  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:10534D013274
Disease Name:stomach cancerStomach Neoplasms
Category:Disease OntologyMeSH
Type:Neoplasms
Define:A gastrointestinal system cancer that is located_in the stomach.Tumors or cancer of the STOMACH.
Alias:gastric cancer//gastric neoplasmStomach Neoplasms//Neoplasm, Stomach//Stomach Neoplasm//Neoplasms, Stomach//Gastric Neoplasms//Gastric Neoplasm//Neoplasm, Gastric//Neoplasms, Gastric//Cancer of Stomach//Stomach Cancers//Gastric Cancer//Cancer, Gastric//Cancers, Gastric//Gastric Cancers//Stomach Cancer//Cancer, Stomach//Cancers, Stomach//Cancer of the Stomach//Gastric Cancer, Familial Diffuse

 

Disease Association Statistics

Total Associated ncRNA Number:1648   
More Information
Causal ncRNA Number:1044
Network:
Top Causal ncRNAs:
NORAD  (Score: 1)
SNHG1  (Score: 1)
UCA1  (Score: 1)
NEAT1  (Score: 1)
MALAT1  (Score: 1)
SNHG12  (Score: 1)
DLX6-AS1  (Score: 1)
UCA1  (Score: 1)
SNHG3  (Score: 1)
H19  (Score: 1)
More Information

 

Evidence Support

Strong Evidence:Western Blot//Flow Cytometry//qRT-PCR//MTT//Luciferase Report Assay//Transwell Assay
Weak Evidence:

 

Reference

[1] PubMed ID:32293550
Disease Name:Stomach Neoplasms
Sample:gastric cancer tissues and cells
Dysfunction Pattern:interaction[sponging miR-490-3p]
Validated Method:Western Blot//Flow Cytometry//qRT-PCR//MTT//Luciferase Report Assay//Transwell Assay
Description:LINC00483 and MAPK1 levels were increased in gastric cancer tissues and cells.Besides, inhibition of LINC00483 decreased xenograft tumor growth by regulating miR-490-3p/MAPK1 axis.
Causality:Yes
Causal Description: Knockdown of LINC00483 or MAPK1 inhibited cells viability, migration and invasion but promoted apoptosis in gastric cancer cells. Moreover, MAPK1 overexpression attenuated the effect of LINC00483 knockdown on gastric cancer development.
Clinical-realted Application: