Entry Detail

General Information

Database ID: LDA0004538
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:CACNA1G-AS1
Full Name:CACNA1G antisense RNA 1
Category:LncRNA
Species:Homo sapiens
Synonyms:CAS1
Chromosome:17
Strand:-
Coordinate:
Start Site(bp):50556207End Site(bp):50562108
External Links:
Ensembl ID:ENSG00000250107
Ensembl Transcript ID:N/A
Entrez Gene:253962.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:10   
More Information
Causal Disease Number:8
Network:
Top Causal Diseases:
Colorectal Neoplasms  (Score: 0.731059)
Carcinoma, Hepatocellular  (Score: 0.731059)
Lymphoma, Large B-Cell, Diffuse  (Score: 0.731059)
Keloid  (Score: 0.731059)
Colorectal Neoplasms  (Score: 0.731059)
Carcinoma, Hepatocellular  (Score: 0.731059)
Lymphoma, Large B-Cell, Diffuse  (Score: 0.731059)
Keloid  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:D007627
Disease Name:Keloid
Category:MeSH
Type:Tissues
Define:A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.
Alias:Keloid//Keloids

 

Disease Association Statistics

Total Associated ncRNA Number:14   
More Information
Causal ncRNA Number:14
Network:
Top Causal ncRNAs:
HOXA11-AS  (Score: 0.985791)
H19  (Score: 0.985791)
HOXA11-AS  (Score: 0.985791)
H19  (Score: 0.985791)
GNAS-AS1  (Score: 0.731059)
CACNA1G-AS1  (Score: 0.731059)
hsa_circ_0043688  (Score: 0.731059)
circNRIP1  (Score: 0.731059)
NEAT1  (Score: 0.731059)
GNAS-AS1  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:CCK8//qRT-PCR//RIP//Flow Cytometry//Luciferase Report Assay//Transwell Assay
Weak Evidence:

 

Reference

[1] PubMed ID:32495824
Disease Name:Keloid
Sample:keloid tissues
Dysfunction Pattern:regulation[miR-205]
Validated Method:CCK8//qRT-PCR//Flow Cytometry//RIP//Luciferase Report Assay//Transwell Assay
Description:CACNA1G-AS1 level was up-regulated in keloid tissues and keloid fibroblasts.CACNA1G-AS1 suppressed miR-205 expression to promote proliferation and invasion and inhibit apoptosis in human keloid fibroblasts.
Causality:Yes
Causal Description:CACNA1G-AS1 overexpression promoted proliferation and invasion and suppressed apoptosis of keloid fibroblasts.
Clinical-realted Application: