Entry Detail

General Information

Database ID: LDA0004757
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Yes

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:SLC16A1-AS1
Full Name:SLC16A1 antisense RNA 1
Category:LncRNA
Species:Homo sapiens
Synonyms:-
Chromosome:1
Strand:+
Coordinate:
Start Site(bp):112956415End Site(bp):112964072
External Links:
Ensembl ID:ENSG00000226419
Ensembl Transcript ID:N/A
Entrez Gene:100506392.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:16   
More Information
Causal Disease Number:16
Network:
Top Causal Diseases:
Glioblastoma  (Score: 0.985791)
Carcinoma, Hepatocellular  (Score: 0.985791)
Squamous Cell Carcinoma of Head and Neck  (Score: 0.985791)
Glioblastoma  (Score: 0.985791)
Carcinoma, Hepatocellular  (Score: 0.985791)
Squamous Cell Carcinoma of Head and Neck  (Score: 0.985791)
Breast Neoplasms  (Score: 0.731059)
Carcinoma, Non-Small-Cell Lung  (Score: 0.731059)
Carcinoma, Renal Cell  (Score: 0.731059)
Triple Negative Breast Neoplasms  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:3744
Disease Name:cervical squamous cell carcinoma
Category:Disease Ontology
Type:Neoplasms
Define:A cervix carcinoma that has_material_basis_in squamous cells of the cervix.
Alias:squamous cell carcinoma of cervix//squamous cell carcinoma of the Cervix Uteri

 

Disease Association Statistics

Total Associated ncRNA Number:52   
More Information
Causal ncRNA Number:50
Network:
Top Causal ncRNAs:
MCM3AP-AS1  (Score: 0.985791)
MCM3AP-AS1  (Score: 0.985791)
MAGI2-AS3  (Score: 0.985791)
MAGI2-AS3  (Score: 0.985791)
SLC16A1-AS1  (Score: 0.731059)
GATA6-AS  (Score: 0.731059)
BLACAT1  (Score: 0.731059)
CASC9-1  (Score: 0.731059)
DGUOK-AS1  (Score: 0.731059)
MACC1-AS1  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:Western Blot//Transfection//CCK8//qRT-PCR//Luciferase Report Assay//Colony Formation Assay
Weak Evidence:

 

Reference

[1] PubMed ID:33603475
Disease Name:cervical squamous cell carcinoma
Sample:CSCC and non-tumor tissue samples
Dysfunction Pattern:Interaction(miR-194/SOCS2 Axis)
Validated Method:Western Blot//Transfection//CCK8//qRT-PCR//Luciferase Report Assay//Colony Formation Assay
Description:SLC16A1-AS1 was down-regulated in CSCC and correlated with poor survival. In addition, SLC16A1-AS1 could sponge miR-194 and increase the expression levels of SOCS2, ultimately inhibiting the proliferation of cervical cancer cells.
Causality:Yes
Causal Description:Overexpression of SLC16A1-AS1 could inhibit the proliferation of cervical cancer cells.
Clinical-realted Application:SLC16A1-AS1 was down-regulated in CSCC and correlated with poor survival.