LncRNADisease3

Entry Detail

General Information

Database ID:	LDA0004800
Species:	Homo sapiens
Confidence Score:	0.731059
Contents:	>> ncRNA Information >> ncRNA Association Statistics >> Disease Information >> Disease Association Statistics >> Evidence Support >> Reference
Causality:	Yes
Clinical Significance:	Unknown

ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:

SCIRT

Full Name:

stem cell inhibitory RNA transcript

Category:

LncRNA

Species:

Homo sapiens

Synonyms:

DATOC-1

Chromosome:

Strand:

Coordinate:

Start Site(bp):

43995723

End Site(bp):

44074652

External Links:

Ensembl ID:	ENSG00000237686
Ensembl Transcript ID:	N/A
Entrez Gene:	101929705.0
NONCODE ID:	N/A
RefSeq Accession:	N/A

ncRNA Association Statistics

Total Associated Disease Number:

8 More Information

Causal Disease Number:

Network:

Top Causal Diseases:

Lung Neoplasms (Score: 0.731059)

Squamous Cell Carcinoma of Head and Neck (Score: 0.731059)

Uterine Cervical Neoplasms (Score: 0.731059)

Atherosclerosis (Score: 0.731059)

Lung Neoplasms (Score: 0.731059)

Squamous Cell Carcinoma of Head and Neck (Score: 0.731059)

Uterine Cervical Neoplasms (Score: 0.731059)

Atherosclerosis (Score: 0.731059)

More Information

Disease Information

	Disease Ontology	MeSH
Disease ID:	DOID:1324	D008175
Disease Name:	lung cancer	Lung Neoplasms
Category:	Disease Ontology	MeSH
Type:		Neoplasms
Define:	A respiratory system cancer that is located_in the lung.	Tumors or cancer of the LUNG.
Alias:		Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung

Disease Association Statistics

Total Associated ncRNA Number:

344 More Information

Causal ncRNA Number:

282

Network:

Top Causal ncRNAs:

OIP5-AS1 (Score: 0.999893)

MNX1-AS1 (Score: 0.999893)

NEAT1 (Score: 0.999893)

MNX1-AS1 (Score: 0.999893)

NEAT1 (Score: 0.999893)

circHIPK3 (Score: 0.985791)

GAS5 (Score: 0.985791)

PCAT1 (Score: 0.985791)

NNT-AS1 (Score: 0.985791)

More Information

Evidence Support

Strong Evidence:	qRT-PCR
Weak Evidence:

Reference

[1] PubMed ID:	34349799
Disease Name:	Lung Neoplasms
Sample:	cancer cell exosomes
Dysfunction Pattern:	Interaction(miR-665)
Validated Method:	qRT-PCR
Description:	We further demonstrated that lncRNA SCIRT was also increased in cancer cell exosomes and may facilitate the exosomal loading of miR-665 with the help of hnRNPA1.
Causality:	Yes
Causal Description:	In addition, we found that miR-665 and SCIRT were significantly upregulated in tumor tissue and plasma of patients with lung cancer, and both of them showed increased expression in metastatic disease samples.
Clinical-realted Application:

LncRNADisease v3.0

Entry Detail