Entry Detail

General Information

Database ID: LDA0004831
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:SNHG1
Full Name:small nucleolar RNA host gene 1
Category:LncRNA
Species:Homo sapiens
Synonyms:LINC00057|NCRNA00057|U22HG|UHG|lncRNA16
Chromosome:11
Strand:-
Coordinate:
Start Site(bp):62851978End Site(bp):62855885
External Links:
Ensembl ID:ENSG00000255717
Ensembl Transcript ID:N/A
Entrez Gene:23642.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:82   
More Information
Causal Disease Number:74
Network:
Top Causal Diseases:
Prostatic Neoplasms  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Leukemia, Myeloid, Acute  (Score: 1)
Stomach Neoplasms  (Score: 1)
Urinary Bladder Neoplasms  (Score: 1)
Urinary Bladder Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Stomach Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:8618
Disease Name:oral cavity cancer
Category:Disease Ontology
Type:Neoplasms
Define:A gastrointestinal system cancer that is located_in the oral cavity.
Alias:malignant neoplasm of floor of mouth

 

Disease Association Statistics

Total Associated ncRNA Number:4   
More Information
Causal ncRNA Number:4
Network:
Top Causal ncRNAs:
SNHG1  (Score: 0.731059)
PTCSC3  (Score: 0.731059)
SNHG1  (Score: 0.731059)
PTCSC3  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:34174971
Disease Name:oral cavity cancer
Sample:
Dysfunction Pattern:regulation[miR-421/HMGB2 axis]
Validated Method:qRT-PCR
Description:In this research, we found that lncRNA SNHG1 was up-regulated in oral cancer. Then we revealed a new mechanism that lncRNA SNHG1 regulated the growth of oral cancer via controlling the miR-421/HMGB2 axis, which provided new therapy for patients with oral cancer.
Causality:Yes
Causal Description:Knockdown of lncRNA SNHG1 would inhibit the proliferation of oral cancer cells.
Clinical-realted Application: