Entry Detail

General Information

Database ID: LDA0006065
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Yes

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:UBA6-DT
Full Name:UBA6 divergent transcript
Category:LncRNA
Species:Homo sapiens
Synonyms:UBA6-AS1
Chromosome:4
Strand:+
Coordinate:
Start Site(bp):67701278End Site(bp):67722505
External Links:
Ensembl ID:ENSG00000248049
Ensembl Transcript ID:N/A
Entrez Gene:550112.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:4   
More Information
Causal Disease Number:4
Network:
Top Causal Diseases:
Ovarian Neoplasms  (Score: 0.731059)
Ovarian Neoplasms  (Score: 0.731059)
Colonic Neoplasms  (Score: 0.548294)
Colonic Neoplasms  (Score: 0.548294)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:2394D010051
Disease Name:ovarian cancerOvarian Neoplasms
Category:Disease OntologyMeSH
Type:Neoplasms
Define:A female reproductive organ cancer that is located_in the ovary.Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
Alias:malignant Ovarian tumor//malignant tumour of ovary//ovarian neoplasm//ovary neoplasm//primary ovarian cancer//tumor of the OvaryOvarian Neoplasms//Neoplasm, Ovarian//Ovarian Neoplasm//Ovary Neoplasms//Neoplasm, Ovary//Neoplasms, Ovary//Ovary Neoplasm//Neoplasms, Ovarian//Ovary Cancer//Cancer, Ovary//Cancers, Ovary//Ovary Cancers//Ovarian Cancer//Cancer, Ovarian//Cancers, Ovarian//Ovarian Cancers//Cancer of Ovary//Cancer of the Ovary

 

Disease Association Statistics

Total Associated ncRNA Number:478   
More Information
Causal ncRNA Number:418
Network:
Top Causal ncRNAs:
PVT1  (Score: 1)
ATB  (Score: 1)
GAS5  (Score: 1)
PVT1  (Score: 1)
KCNQ1OT1  (Score: 1)
ATB  (Score: 1)
XIST  (Score: 1)
SNHG3  (Score: 1)
NEAT1  (Score: 1)
KCNQ1OT1  (Score: 1)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR//MeRIP
Weak Evidence:

 

Reference

[1] PubMed ID:34951345
Disease Name:Ovarian Neoplasms
Sample:OC tissues
Dysfunction Pattern:Interaction(RBM15/IGF2BP1)
Validated Method:qRT-PCR//MeRIP
Description:Here, we found that UBA6-AS1 directly associated with UBA6 mRNA and inhibited its decay. Moreover, UBA6-AS1 positively correlated with UBA6 expression in OC tissues.
Causality:Yes
Causal Description: Functionally, UBA6-AS1 suppressed the proliferation, migration and invasion of OC cells via UBA6.
Clinical-realted Application:Downregulation of UBA6-AS1 or UBA6 expression indicated poor.