Entry Detail

General Information

Database ID: LDA0006228
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:ZFPM2-AS1
Full Name:ZFPM2 antisense RNA 1
Category:LncRNA
Species:Homo sapiens
Synonyms:SCAT3
Chromosome:8
Strand:-
Coordinate:
Start Site(bp):105780410End Site(bp):106060503
External Links:
Ensembl ID:ENSG00000251003
Ensembl Transcript ID:N/A
Entrez Gene:102723356.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:24   
More Information
Causal Disease Number:24
Network:
Top Causal Diseases:
Carcinoma, Hepatocellular  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Retinoblastoma  (Score: 0.999893)
Retinoblastoma  (Score: 0.999893)
Adenocarcinoma of Lung  (Score: 0.985791)
Adenocarcinoma of Lung  (Score: 0.985791)
Esophageal Squamous Cell Carcinoma  (Score: 0.731059)
Glioma  (Score: 0.731059)
Nasopharyngeal carcinoma  (Score: 0.731059)
Carcinoma, Renal Cell  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:D055752
Disease Name:Small Cell Lung Carcinoma
Category:MeSH
Type:Neoplasms
Define:A form of highly malignant lung cancer that is composed of small ovoid cells (SMALL CELL CARCINOMA).
Alias:Small Cell Lung Carcinoma//Small Cell Lung Cancer//Oat Cell Lung Cancer//Small Cell Cancer Of The Lung//Carcinoma, Small Cell Lung//Oat Cell Carcinoma of Lung

 

Disease Association Statistics

Total Associated ncRNA Number:28   
More Information
Causal ncRNA Number:24
Network:
Top Causal ncRNAs:
circPVT1  (Score: 0.731059)
KCNQ1OT1  (Score: 0.731059)
LUADT1  (Score: 0.731059)
LINC01555  (Score: 0.731059)
LINC01116  (Score: 0.731059)
CASC11  (Score: 0.731059)
ZFPM2-AS1  (Score: 0.731059)
MCM3AP-AS1  (Score: 0.731059)
NEF  (Score: 0.731059)
HIF1A-AS2  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:RNA Pull-Down//Transwell Assay//Wound Healing Assay//CCK8//qRT-PCR//RIP//Luciferase Report Assay//Colony Formation Assay//EdU Staining//ChIP
Weak Evidence:

 

Reference

[1] PubMed ID:32280300
Disease Name:Small Cell Lung Carcinoma
Sample:SCLC tissues and cells
Dysfunction Pattern:regulation[TRAF4]
Validated Method:RNA Pull-Down//ChIP//Wound Healing Assay//CCK8//qRT-PCR//RIP//Luciferase Report Assay//Colony Formation Assay//EdU Staining//Transwell Assay
Description:ZFPM2-AS1 was significantly upregulated in SCLC tissues and cells. Finally, TRAF4 could countervail ZFPM2-AS1 downregulation-mediated function on SCLC cell proliferation and invasion in vitro and tumor growth in vivo.
Causality:Yes
Causal Description:ZFPM2-AS1 deficiency attenuated SCLC cell proliferation, invasion and migration.
Clinical-realted Application: