| | Disease Ontology | MeSH |
| Disease ID: | DOID:10652 | D000544 |
| Disease Name: | Alzheimer's disease | Alzheimer Disease |
| Category: | Disease Ontology | MeSH |
| Type: | | Nervous System Diseases |
| Define: | A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. | A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) |
| Alias: | Alzheimer disease//Alzheimers dementia | Alzheimer Disease//Alzheimer Dementia//Alzheimer Dementias//Dementia, Alzheimer//Alzheimer's Disease//Dementia, Senile//Senile Dementia//Dementia, Alzheimer Type//Alzheimer Type Dementia//Alzheimer-Type Dementia (ATD)//Alzheimer Type Dementia (ATD)//Dementia, Alzheimer-Type (ATD)//Alzheimer Type Senile Dementia//Primary Senile Degenerative Dementia//Dementia, Primary Senile Degenerative//Alzheimer Sclerosis//Sclerosis, Alzheimer//Alzheimer Syndrome//Alzheimer's Diseases//Alzheimer Diseases//Alzheimers Diseases//Senile Dementia, Alzheimer Type//Acute Confusional Senile Dementia//Senile Dementia, Acute Confusional//Dementia, Presenile//Presenile Dementia//Alzheimer Disease, Late Onset//Late Onset Alzheimer Disease//Alzheimer's Disease, Focal Onset//Focal Onset Alzheimer's Disease//Familial Alzheimer Disease (FAD)//Alzheimer Disease, Familial (FAD)//Familial Alzheimer Diseases (FAD)//Alzheimer Disease, Early Onset//Early Onset Alzheimer Disease//Presenile Alzheimer Dementia |
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