Entry Detail

General Information

Database ID: LDA0006370
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:SOD2
Full Name:superoxide dismutase 2
Category:LncRNA
Species:Homo sapiens
Synonyms:GC1|GClnc1|IPO-B|IPOB|MNSOD|MVCD6|Mn-SOD
Chromosome:6
Strand:-
Coordinate:
Start Site(bp):159669069End Site(bp):159762281
External Links:
Ensembl ID:ENSG00000291237
Ensembl Transcript ID:N/A
Entrez Gene:6648.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:10   
More Information
Causal Disease Number:10
Network:
Top Causal Diseases:
Ovarian Neoplasms  (Score: 0.731059)
Colorectal Neoplasms  (Score: 0.731059)
Carcinoma, Ovarian Epithelial  (Score: 0.731059)
Urinary Bladder Neoplasms  (Score: 0.731059)
Carcinoma, Non-Small-Cell Lung  (Score: 0.731059)
Ovarian Neoplasms  (Score: 0.731059)
Colorectal Neoplasms  (Score: 0.731059)
Carcinoma, Ovarian Epithelial  (Score: 0.731059)
Urinary Bladder Neoplasms  (Score: 0.731059)
Carcinoma, Non-Small-Cell Lung  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:2394D010051
Disease Name:ovarian cancerOvarian Neoplasms
Category:Disease OntologyMeSH
Type:Neoplasms
Define:A female reproductive organ cancer that is located_in the ovary.Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
Alias:malignant Ovarian tumor//malignant tumour of ovary//ovarian neoplasm//ovary neoplasm//primary ovarian cancer//tumor of the OvaryOvarian Neoplasms//Neoplasm, Ovarian//Ovarian Neoplasm//Ovary Neoplasms//Neoplasm, Ovary//Neoplasms, Ovary//Ovary Neoplasm//Neoplasms, Ovarian//Ovary Cancer//Cancer, Ovary//Cancers, Ovary//Ovary Cancers//Ovarian Cancer//Cancer, Ovarian//Cancers, Ovarian//Ovarian Cancers//Cancer of Ovary//Cancer of the Ovary

 

Disease Association Statistics

Total Associated ncRNA Number:478   
More Information
Causal ncRNA Number:418
Network:
Top Causal ncRNAs:
PVT1  (Score: 1)
ATB  (Score: 1)
GAS5  (Score: 1)
PVT1  (Score: 1)
KCNQ1OT1  (Score: 1)
ATB  (Score: 1)
XIST  (Score: 1)
SNHG3  (Score: 1)
NEAT1  (Score: 1)
KCNQ1OT1  (Score: 1)
More Information

 

Evidence Support

Strong Evidence:Western Blot//ISH//CCK8//qRT-PCR//RIP//Luciferase Report Assay//Transwell Assay
Weak Evidence:

 

Reference

[1] PubMed ID:33207861
Disease Name:Ovarian Neoplasms
Sample:OC tissues
Dysfunction Pattern:regulation[p53 signaling pathway]
Validated Method:Western Blot//ISH//CCK8//qRT-PCR//RIP//Luciferase Report Assay//Transwell Assay
Description:The expression of lncRNA H19 GClnc1 was markedly higher in OC samples than the related normal tissues.To sum up, LncRNA GClnc1 contributes to the progression of OC by regulating p53 signaling pathway.
Causality:Yes
Causal Description:In addition, the lncRNA GClnc1 overexpression promoted the cell proliferation and migration in vitro.
Clinical-realted Application: