Entry Detail

General Information

Database ID: LDA0006552
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:SNHG6
Full Name:small nucleolar RNA host gene 6
Category:LncRNA
Species:Homo sapiens
Synonyms:HBII-276HG|NCRNA00058|U87HG
Chromosome:8
Strand:-
Coordinate:
Start Site(bp):66921690End Site(bp):66925541
External Links:
Ensembl ID:ENSG00000245910
Ensembl Transcript ID:N/A
Entrez Gene:641638.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:56   
More Information
Causal Disease Number:46
Network:
Top Causal Diseases:
Breast Neoplasms  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Esophageal Squamous Cell Carcinoma  (Score: 1)
Carcinoma, Non-Small-Cell Lung  (Score: 1)
Esophageal Squamous Cell Carcinoma  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Carcinoma, Non-Small-Cell Lung  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:C564300
Disease Name:Amyotrophic Lateral Sclerosis 7
Category:MeSH
Type:Musculoskeletal Diseases
Define:
Alias:

 

Disease Association Statistics

Total Associated ncRNA Number:2   
More Information
Causal ncRNA Number:2
Network:
Top Causal ncRNAs:
SNHG6  (Score: 0.731059)
SNHG6  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR//Transfection//Cell Cycle Assay
Weak Evidence:

 

Reference

[1] PubMed ID:35096086
Disease Name:Amyotrophic Lateral Sclerosis 7
Sample:tumor and non-tumor tissues.
Dysfunction Pattern:Expression(highly expressed)
Validated Method:qRT-PCR//Transfection//Cell Cycle Assay
Description:SNHG6 was more expressed in CRC tumors than non-tumor tissues. In tumor tissues, SNHG6 upregulation and tumors' grade progression were concurrent. SNHG6 was upregulated in cases with lymphovascular invasion than in cases with perineural invasion.
Causality:Yes
Causal Description:The knockdown of SNHG6 conduced to G1 arrest in CRC cells, more noticeably in high-grade ones.
Clinical-realted Application: