Entry Detail

General Information

Database ID: LDA0006796
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:TFDP1
Full Name:transcription factor Dp-1
Category:LncRNA
Species:Homo sapiens
Synonyms:DILC|DP1|DRTF1|Dp-1
Chromosome:13
Strand:+
Coordinate:
Start Site(bp):113584688End Site(bp):113641473
External Links:
Ensembl ID:ENSG00000198176
Ensembl Transcript ID:N/A
Entrez Gene:7027.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:8   
More Information
Causal Disease Number:2
Network:
Top Causal Diseases:
Urinary Bladder Neoplasms  (Score: 0.731059)
Urinary Bladder Neoplasms  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:11054D001749
Disease Name:urinary bladder cancerUrinary Bladder Neoplasms
Category:Disease OntologyMeSH
Type:Neoplasms
Define:An urinary system cancer that results_in malignant growth located_in the urinary bladder.Tumors or cancer of the URINARY BLADDER.
Alias:bladder cancer//tumor of the bladderUrinary Bladder Neoplasms//Neoplasm, Urinary Bladder//Urinary Bladder Neoplasm//Bladder Tumors//Bladder Tumor//Tumor, Bladder//Tumors, Bladder//Neoplasms, Bladder//Bladder Neoplasms//Bladder Neoplasm//Neoplasm, Bladder//Urinary Bladder Cancer//Cancer, Urinary Bladder//Malignant Tumor of Urinary Bladder//Cancer of the Bladder//Bladder Cancer//Bladder Cancers//Cancer, Bladder//Cancer of Bladder

 

Disease Association Statistics

Total Associated ncRNA Number:604   
More Information
Causal ncRNA Number:428
Network:
Top Causal ncRNAs:
SNHG1  (Score: 1)
SNHG1  (Score: 1)
TINCR  (Score: 0.999893)
PCAT6  (Score: 0.999893)
GAS5  (Score: 0.999893)
MILIP  (Score: 0.999893)
TUG1  (Score: 0.999893)
circCEP128  (Score: 0.999893)
XIST  (Score: 0.999893)
CASC9  (Score: 0.999893)
More Information

 

Evidence Support

Strong Evidence:Western Blot//Migration Assay//CCK8//Flow Cytometry//qRT-PCR//Luciferase Report Assay//Invasion Assay
Weak Evidence:

 

Reference

[1] PubMed ID:31176734
Disease Name:Urinary Bladder Neoplasms
Sample:bladder cancer tissues
Dysfunction Pattern:Regulation[STAT3 signaling]
Validated Method:Western Blot//Migration Assay//CCK8//Flow Cytometry//qRT-PCR//Luciferase Report Assay//Invasion Assay
Description:In the present study, we for first found that lnc-DILC was downregulated in human bladder cancer tissues.Taken together, our results suggest that lnc-DILC is a novel bladder tumor suppressor and indicate that lnc-DILC inhibits BC progression via inactivating STAT3 signaling.
Causality:Yes
Causal Description: Lnc-DILC overexpression suppressed the proliferation, metastasis and expansion of bladder cancer stem cells (CSCs).
Clinical-realted Application: