Entry Detail


General Information

Database ID: LDA0006811
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:TARID
Full Name:TCF21 antisense RNA inducing promoter demethylation
Category:LncRNA
Species:Homo sapiens
Synonyms:EYA4-AS1
Chromosome:6
Strand:-
Coordinate:
Start Site(bp):133502252End Site(bp):133889006
External Links:
Ensembl ID:ENSG00000227954
Ensembl Transcript ID:N/A
Entrez Gene:100507308.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:6   
More Information
Causal Disease Number:2
Network:
Top Causal Diseases:
Coronary Artery Disease  (Score: 0.731059)
Coronary Artery Disease  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:3393D003324
Disease Name:coronary artery diseaseCoronary Artery Disease
Category:Disease OntologyMeSH
Type:Cardiovascular Diseases
Define:An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
Alias:CHD//Coronary disease//coronary arteriosclerosis//coronary heart diseaseCoronary Artery Disease//Artery Disease, Coronary//Artery Diseases, Coronary//Coronary Artery Diseases//Left Main Coronary Artery Disease//Left Main Disease//Left Main Diseases//Left Main Coronary Disease//Coronary Arteriosclerosis//Arterioscleroses, Coronary//Coronary Arterioscleroses//Atherosclerosis, Coronary//Atheroscleroses, Coronary//Coronary Atheroscleroses//Coronary Atherosclerosis//Arteriosclerosis, Coronary

 

Disease Association Statistics

Total Associated ncRNA Number:134   
More Information
Causal ncRNA Number:24
Network:
Top Causal ncRNAs:
MALAT1  (Score: 1)
MALAT1  (Score: 1)
LINC00968  (Score: 0.985791)
LINC00968  (Score: 0.985791)
uc003pxg.1  (Score: 0.731059)
GAS5  (Score: 0.731059)
AGAP2-AS1  (Score: 0.731059)
circLDLR  (Score: 0.731059)
circNPHP4  (Score: 0.731059)
NEAT1  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:Cell Proliferation Assay//Cell Cycle Assay//Genotyping//qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:35304681
Disease Name:Coronary Artery Disease
Sample:Chinese Han population
Dysfunction Pattern:Mutation(rs2327433)
Validated Method:Cell Proliferation Assay//Cell Cycle Assay//Genotyping//qRT-PCR
Description:SNP rs2327433 in lncRNA TARID was associated with CAD risk and the severity of CAD in the Chinese Han population.
Causality:Yes
Causal Description:We found that TARID silencing regulated cell proliferation and altered cell cycle progression by induced upregulation of CDK1 and PCNA.
Clinical-realted Application: