Entry Detail

General Information

Database ID: LDA0007155
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Yes
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:MILIP
Full Name:MYC inducible lncRNA inactivating p53
Category:LncRNA
Species:Homo sapiens
Synonyms:MAFG-AS1|MAFG-DT
Chromosome:17
Strand:+
Coordinate:
Start Site(bp):81927829End Site(bp):81930753
External Links:
Ensembl ID:ENSG00000265688
Ensembl Transcript ID:N/A
Entrez Gene:92659.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:30   
More Information
Causal Disease Number:30
Network:
Top Causal Diseases:
Breast Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Carcinoma, Hepatocellular  (Score: 0.999893)
Urinary Bladder Neoplasms  (Score: 0.999893)
Carcinoma, Hepatocellular  (Score: 0.999893)
Colorectal Neoplasms  (Score: 0.999893)
Colorectal Neoplasms  (Score: 0.999893)
Urinary Bladder Neoplasms  (Score: 0.999893)
Adenocarcinoma of Lung  (Score: 0.985791)
Adenocarcinoma of Lung  (Score: 0.985791)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:4006
Disease Name:bladder urothelial carcinoma
Category:Disease Ontology
Type:Neoplasms
Define:A bladder carcinoma that has_material_basis_in transitional cells located_in the lining of the bladder.
Alias:bladder transitional cell carcinoma//transitional cell carcinoma of bladder//urinary bladder urothelial carcinoma//urothelial bladder carcinoma

 

Disease Association Statistics

Total Associated ncRNA Number:10   
More Information
Causal ncRNA Number:2
Network:
Top Causal ncRNAs:
MILIP  (Score: 0.731059)
MILIP  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:Western Blot//Wound Healing Assay//Co-IP//Colony Formation Assay//qRT-PCR//FISH//RIP//MTT//IP//IHC//Transwell Assay
Weak Evidence:

 

Reference

[1] PubMed ID:33377647
Disease Name:bladder urothelial carcinoma
Sample:BUC tissues
Dysfunction Pattern:regulation[HuR/PTBP1 axis]
Validated Method:IHC//Western Blot//Wound Healing Assay//Co-IP//qRT-PCR//FISH//RIP//MTT//IP//Colony Formation Assay//Transwell Assay
Description:Here, we found that the lncRNA MAFG-AS1, which is highly expressed in BUC, is correlated with aggressive characteristics and poor prognosis of BUC. In conclusion, these findings indicate that MAFG-AS1 promotes the progression of BUC via regulation of the HUR/PTBP1 axis.
Causality:Yes
Causal Description:We demonstrate that MAFG-AS1 can promote BUC proliferation, invasion, metastasis, and epithelial-mesenchymal transition in vitro and in vivo.
Clinical-realted Application: