Entry Detail

General Information

Database ID: LDA0015372
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:MAGI2-AS3
Full Name:MAGI2 antisense RNA 3
Category:LncRNA
Species:Homo sapiens
Synonyms:-
Chromosome:7
Strand:+
Coordinate:
Start Site(bp):79452957End Site(bp):79471208
External Links:
Ensembl ID:ENSG00000234456
Ensembl Transcript ID:N/A
Entrez Gene:100505881.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:28   
More Information
Causal Disease Number:22
Network:
Top Causal Diseases:
Carcinoma, Non-Small-Cell Lung  (Score: 1)
Carcinoma, Non-Small-Cell Lung  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
cervical squamous cell carcinoma  (Score: 0.985791)
cervical squamous cell carcinoma  (Score: 0.985791)
Prostatic Neoplasms  (Score: 0.985791)
Urinary Bladder Neoplasms  (Score: 0.985791)
Urinary Bladder Neoplasms  (Score: 0.985791)
Prostatic Neoplasms  (Score: 0.985791)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:90D055959
Disease Name:degenerative disc diseaseIntervertebral Disc Degeneration
Category:Disease OntologyMeSH
Type:Musculoskeletal Diseases
Define:A bone deterioration disease that has_material_basis_in gradual dehydration and tears located_in intervertebral disc.Degenerative changes in the INTERVERTEBRAL DISC due to aging or structural damage, especially to the vertebral end-plates.
Alias:cervical disc degenerative disease//intervertebral disc degeneration//lumbar disc degeneration//vertebral disc diseaseIntervertebral Disc Degeneration//Degeneration, Intervertebral Disc//Disc Degeneration, Intervertebral//Intervertebral Disc Degenerations//Disc Degeneration//Degeneration, Disc//Disc Degenerations//Intervertebral Disk Degeneration//Degeneration, Intervertebral Disk//Disk Degeneration, Intervertebral//Intervertebral Disk Degenerations//Disk Degeneration//Degeneration, Disk//Disk Degenerations//Disk Degradation//Degradation, Disk//Disk Degradations//Degenerative Disc Disease//Degenerative Disc Diseases//Disc Disease, Degenerative//Disc Degradation//Degradation, Disc//Disc Degradations//Degenerative Intervertebral Discs//Degenerative Intervertebral Disc//Disc, Degenerative Intervertebral//Intervertebral Disc, Degenerative//Degenerative Intervertebral Disks//Degenerative Intervertebral Disk//Disk, Degenerative Intervertebral//Intervertebral Disk, Degenerative

 

Disease Association Statistics

Total Associated ncRNA Number:20   
More Information
Causal ncRNA Number:14
Network:
Top Causal ncRNAs:
ITCH  (Score: 0.731059)
MALAT1  (Score: 0.731059)
CAHM  (Score: 0.731059)
PART1  (Score: 0.731059)
RMRP  (Score: 0.731059)
circGLCE  (Score: 0.731059)
NRAD1  (Score: 0.731059)
ITCH  (Score: 0.731059)
MALAT1  (Score: 0.731059)
CAHM  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR//Western Blot
Weak Evidence:

 

Reference

[1] PubMed ID:32143617
Disease Name:Intervertebral Disc Degeneration
Sample:plasma
Dysfunction Pattern:Expression[lower expressed]
Validated Method:qRT-PCR//Western Blot
Description:The expression levels of plasma lncRNA MAGI2-AS3 were lower in IDD patients compared to that in the control group.
Causality:No
Causal Description:
Clinical-realted Application: