Entry Detail

General Information

Database ID: LDA0015922
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:NEF
Full Name:S100 calcium binding protein B
Category:LncRNA
Species:Homo sapiens
Synonyms:NEF|S100|S100-B|S100beta
Chromosome:21
Strand:-
Coordinate:
Start Site(bp):46598604End Site(bp):46605082
External Links:
Ensembl ID:N/A
Ensembl Transcript ID:N/A
Entrez Gene:6285.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:20   
More Information
Causal Disease Number:18
Network:
Top Causal Diseases:
Thyroid Cancer, Papillary  (Score: 0.731059)
Small Cell Lung Carcinoma  (Score: 0.731059)
Cholangiocarcinoma  (Score: 0.731059)
cervical squamous cell carcinoma  (Score: 0.731059)
stomach carcinoma  (Score: 0.731059)
Squamous Cell Carcinoma of Head and Neck  (Score: 0.731059)
Triple Negative Breast Neoplasms  (Score: 0.731059)
Glioma  (Score: 0.731059)
Esophageal Squamous Cell Carcinoma  (Score: 0.731059)
Thyroid Cancer, Papillary  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:D015663
Disease Name:Osteoporosis, Postmenopausal
Category:MeSH
Type:Musculoskeletal Diseases
Define:Metabolic disorder associated with fractures of the femoral neck, vertebrae, and distal forearm. It occurs commonly in women within 15-20 years after menopause, and is caused by factors associated with menopause including estrogen deficiency.
Alias:Osteoporosis, Postmenopausal//Perimenopausal Bone Loss//Bone Loss, Postmenopausal//Bone Losses, Postmenopausal//Postmenopausal Bone Losses//Osteoporosis, Post-Menopausal//Osteoporoses, Post-Menopausal//Osteoporosis, Post Menopausal//Post-Menopausal Osteoporoses//Post-Menopausal Osteoporosis//Postmenopausal Osteoporosis//Osteoporoses, Postmenopausal//Postmenopausal Osteoporoses//Bone Loss, Perimenopausal//Bone Losses, Perimenopausal//Perimenopausal Bone Losses//Postmenopausal Bone Loss

 

Disease Association Statistics

Total Associated ncRNA Number:16   
More Information
Causal ncRNA Number:4
Network:
Top Causal ncRNAs:
CRNDE  (Score: 0.731059)
hsa_circ_0006859  (Score: 0.731059)
CRNDE  (Score: 0.731059)
hsa_circ_0006859  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:31220986
Disease Name:Osteoporosis, Postmenopausal
Sample:blood
Dysfunction Pattern:Expression[lower expressed]
Validated Method:qRT-PCR
Description:We showed that plasma lncRNA-NEF was downregulated and plasma IL-6 was upregulated in postmenopausal osteoporosis patients compared with healthy controls.
Causality:No
Causal Description:
Clinical-realted Application: