Entry Detail

General Information

Database ID: LDA0016016
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:MIR329-1
Full Name:N/A
Category:LncRNA
Species:Homo sapiens
Synonyms:N/A
Chromosome:N/A
Strand:N/A
Coordinate:
Start Site(bp):0End Site(bp):0
External Links:
Ensembl ID:N/A
Ensembl Transcript ID:N/A
Entrez Gene:N/A
NONCODE ID:N/A
RefSeq Accession:NR_029967.1

 

ncRNA Association Statistics

Total Associated Disease Number:2   
More Information
Causal Disease Number:0
Network:
Top Causal Diseases:
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:0081292D000070642
Disease Name:traumatic brain injuryBrain Injuries, Traumatic
Category:Disease OntologyMeSH
Type:Nervous System Diseases
Define:A brain disease that is characterized by brain dysfunction caused by an outside force, usually a violent blow to the head.A form of acquired brain injury which occurs when a sudden trauma causes damage to the brain.
Alias:Brain Injuries, Traumatic//Brain Injury, Traumatic//Traumatic Brain Injuries//Trauma, Brain//Brain Trauma//Brain Traumas//Traumas, Brain//TBI (Traumatic Brain Injury)//Encephalopathy, Traumatic//Encephalopathies, Traumatic//Traumatic Encephalopathies//Injury, Brain, Traumatic//Traumatic Encephalopathy//TBIs (Traumatic Brain Injuries)//TBI (Traumatic Brain Injuries)//Traumatic Brain Injury

 

Disease Association Statistics

Total Associated ncRNA Number:22   
More Information
Causal ncRNA Number:2
Network:
Top Causal ncRNAs:
Malat1  (Score: 0.985791)
Malat1  (Score: 0.985791)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:30632503
Disease Name:Brain Injuries, Traumatic
Sample:Brain tissues
Dysfunction Pattern:Expression[lower expressed]
Validated Method:qRT-PCR//Microarray
Description:LncRNA and mRNA expression profiles were detected in three TBI and three control groups. Volcano plot filtering identified 99 differentially expressed lncRNAs (P < 0.05, fold change > 1.2) (Figure ​1A1A and ​andB).B). Among them, 43 lncRNAs were up-regulated and 56 lncRNAs were down-regulated. In the TBI group, n333955, n332943, n335470, ENST00000384390, and n341115 were the five most significantly up-regulated lncRNAs. While, TCONS_00018733-XLOC_008489, OTTHUMT00000076953, NR_029967, ENST00000433249, and n381234 were the five most significantly down-regulated lncRNAs (Table 3). Next, we compared mRNA expression profiles of the TBI group with the control group.
Causality:No
Causal Description:
Clinical-realted Application: