Entry Detail

General Information

Database ID: LDA0016178
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Yes

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:LINC00472
Full Name:long intergenic non-protein coding RNA 472
Category:LncRNA
Species:Homo sapiens
Synonyms:C6orf155|P53RRA
Chromosome:6
Strand:-
Coordinate:
Start Site(bp):71407864End Site(bp):71420745
External Links:
Ensembl ID:ENSG00000233237
Ensembl Transcript ID:N/A
Entrez Gene:79940.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:18   
More Information
Causal Disease Number:14
Network:
Top Causal Diseases:
Squamous Cell Carcinoma of Head and Neck  (Score: 0.731059)
Osteosarcoma  (Score: 0.731059)
Triple Negative Breast Neoplasms  (Score: 0.731059)
Acute Hepatic Injury  (Score: 0.731059)
Carcinoma, Hepatocellular  (Score: 0.731059)
Breast Neoplasms  (Score: 0.731059)
Stomach Neoplasms  (Score: 0.731059)
Squamous Cell Carcinoma of Head and Neck  (Score: 0.731059)
Osteosarcoma  (Score: 0.731059)
Triple Negative Breast Neoplasms  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:3910D000077192
Disease Name:lung adenocarcinomaAdenocarcinoma of Lung
Category:Disease OntologyMeSH
Type:Neoplasms
Define:A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.A carcinoma originating in the lung and the most common lung cancer type in never-smokers. Malignant cells exhibit distinct features such as glandular epithelial, or tubular morphology. Mutations in KRAS, EGFR, BRAF, and ERBB2 genes are associated with this cancer.
Alias:bronchogenic lung adenocarcinoma//nonsmall cell adenocarcinomaAdenocarcinoma of Lung//Lung Adenocarcinomas//Lung Adenocarcinoma//Adenocarcinoma, Lung//Adenocarcinomas, Lung

 

Disease Association Statistics

Total Associated ncRNA Number:656   
More Information
Causal ncRNA Number:386
Network:
Top Causal ncRNAs:
LINC00665  (Score: 1)
LINC00511  (Score: 1)
FAM83A-AS1  (Score: 1)
LINC00665  (Score: 1)
LINC00511  (Score: 1)
FAM83A-AS1  (Score: 1)
CCAT1  (Score: 0.999893)
H19  (Score: 0.999893)
SNHG17  (Score: 0.999893)
LINC00467  (Score: 0.999893)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR//RNA Pull-Down//RIP
Weak Evidence:

 

Reference

[1] PubMed ID:33144579
Disease Name:Adenocarcinoma of Lung
Sample:lung adenocarcinoma tissues
Dysfunction Pattern:interaction[binding to YBX1]
Validated Method:qRT-PCR//RNA Pull-Down//RIP
Description:LINC00472 expression in lung adenocarcinoma tissues was significantly lower and tightly associated with patient prognosis and TNM clinical stages in lung adenocarcinoma.These results indicated that LINC00472 inhibited the cell EMT process by binding to YBX1, and affected the mechanical properties of the cell, ultimately inhibited its ability to invade and metastasize.
Causality:No
Causal Description:
Clinical-realted Application:LINC00472 expression in lung adenocarcinoma tissues was significantly lower and tightly associated with patient prognosis and TNM clinical stages in lung adenocarcinoma.