Entry Detail

General Information

Database ID: LDA0016339
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:IFNG-AS1
Full Name:IFNG antisense RNA 1
Category:LncRNA
Species:Homo sapiens
Synonyms:GS1-410F4.2|NEST|Tmevpg1
Chromosome:12
Strand:+
Coordinate:
Start Site(bp):67989445End Site(bp):68021327
External Links:
Ensembl ID:ENSG00000255733
Ensembl Transcript ID:N/A
Entrez Gene:100885789.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:12   
More Information
Causal Disease Number:2
Network:
Top Causal Diseases:
Colonic Neoplasms  (Score: 0.731059)
Colonic Neoplasms  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:8924D016553
Disease Name:autoimmune thrombocytopenic purpuraPurpura, Thrombocytopenic, Idiopathic
Category:Disease OntologyMeSH
Type:Hemic and Lymphatic Diseases
Define:A primary thrombocytopenia that involves relatively few platelets in blood as a result of autoantibodies.Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
Alias:Immune thrombocytopenic purpura//idiopathic thrombocytopenic purpura//primary thrombocytopenic purpuraPurpura, Thrombocytopenic, Idiopathic//Idiopathic Thrombocytopenic Purpura//Idiopathic Thrombocytopenic Purpuras//Purpura, Idiopathic Thrombocytopenic//Purpuras, Idiopathic Thrombocytopenic//Thrombocytopenic Purpura, Idiopathic//Thrombocytopenic Purpuras, Idiopathic//Immune Thrombocytopenic Purpura//Immune Thrombocytopenic Purpuras//Purpura, Immune Thrombocytopenic//Purpuras, Immune Thrombocytopenic//Thrombocytopenic Purpura, Immune//Thrombocytopenic Purpuras, Immune//Immune Thrombocytopenia//Immune Thrombocytopenias//Thrombocytopenia, Immune//Thrombocytopenias, Immune//Thrombocytopenic Purpura, Autoimmune//Werlhof Disease//Disease, Werlhof//Werlhof's Disease//Disease, Werlhof's//Werlhofs Disease//Autoimmune Thrombocytopenia//Autoimmune Thrombocytopenias//Thrombocytopenia, Autoimmune//Thrombocytopenias, Autoimmune//Autoimmune Thrombocytopenic Purpura//Autoimmune Thrombocytopenic Purpuras//Purpura, Autoimmune Thrombocytopenic//Purpuras, Autoimmune Thrombocytopenic//Purpura, Thrombocytopenic, Autoimmune

 

Disease Association Statistics

Total Associated ncRNA Number:12   
More Information
Causal ncRNA Number:2
Network:
Top Causal ncRNAs:
PVT1  (Score: 0.731059)
PVT1  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:36310591
Disease Name:Purpura, Thrombocytopenic, Idiopathic
Sample:blood samples from children with ITP
Dysfunction Pattern:Expression(highly expressed)
Validated Method:qRT-PCR
Description:There were overexpressed lncRNAs IFNG-AS1 and GAS5 in serum of childhood ITP patients [(median (IQR) = 3.08 (0.2-22.39) and 4.19 (0.9-16.91) respectively, Also, significant higher IFNG-AS1 and GAS5 (p < 0.05) were present in persistent ITP (3-12 months) [ median (IQR) = 4.58 (0.31-22.39) and 3.77 (0.87-12.36) respectively] or chronic ITP (>12 months) [ median (IQR) = 5.6 (0.25-12.59) and 5.61 (1.15-16.91) respectively] when compared to newly diagnosed <3 months patients [IFNG-AS1 median (IQR) = 1.21 (0.2-8.95), and GAS5 median (IQR) = 1.07 (0.09-3.55)]
Causality:No
Causal Description:
Clinical-realted Application: