Entry Detail

General Information

Database ID: LDA0016394
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:HOTTIP
Full Name:HOXA distal transcript antisense RNA
Category:LncRNA
Species:Homo sapiens
Synonyms:HOXA-AS6|HOXA13-AS1|NCRNA00213
Chromosome:7
Strand:+
Coordinate:
Start Site(bp):27200421End Site(bp):27207259
External Links:
Ensembl ID:ENSG00000243766
Ensembl Transcript ID:N/A
Entrez Gene:100316868.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:38   
More Information
Causal Disease Number:30
Network:
Top Causal Diseases:
Ovarian Neoplasms  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Ovarian Neoplasms  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Squamous Cell Carcinoma of Head and Neck  (Score: 0.999893)
Squamous Cell Carcinoma of Head and Neck  (Score: 0.999893)
Osteosarcoma  (Score: 0.985791)
Thyroid Cancer, Papillary  (Score: 0.985791)
Thyroid Cancer, Papillary  (Score: 0.985791)
Osteosarcoma  (Score: 0.985791)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:D018270
Disease Name:Carcinoma, Ductal, Breast
Category:MeSH
Type:Neoplasms
Define:An invasive (infiltrating) CARCINOMA of the mammary ductal system (MAMMARY GLANDS) in the human BREAST.
Alias:Carcinoma, Ductal, Breast//Carcinoma, Invasive Ductal, Breast//Invasive Ductal Carcinoma, Breast//Carcinoma, Infiltrating Duct//Carcinomas, Infiltrating Duct//Carcinoma, Mammary Ductal//Carcinomas, Mammary Ductal//Mammary Ductal Carcinomas//Mammary Ductal Carcinoma

 

Disease Association Statistics

Total Associated ncRNA Number:8   
More Information
Causal ncRNA Number:0
Network:
Top Causal ncRNAs:
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:32442909
Disease Name:Carcinoma, Ductal, Breast
Sample:Plasma
Dysfunction Pattern:Expression[highly expressed]
Validated Method:qRT-PCR
Description:Plasma TINCR, HOTTIP, and SPRY4-IT1 upregulation and ANCR downregulation were observed in SSc patients compared with controls.
Causality:No
Causal Description:
Clinical-realted Application: