Entry Detail


General Information

Database ID: LDA0016475
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Yes

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:LINC00311
Full Name:long intergenic non-protein coding RNA 311
Category:LncRNA
Species:Homo sapiens
Synonyms:NCRNA00311|TMEM148
Chromosome:16
Strand:+
Coordinate:
Start Site(bp):85282958End Site(bp):85288082
External Links:
Ensembl ID:ENSG00000179219
Ensembl Transcript ID:N/A
Entrez Gene:197196.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:2   
More Information
Causal Disease Number:0
Network:
Top Causal Diseases:
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:7147D013167
Disease Name:ankylosing spondylitisSpondylitis, Ankylosing
Category:Disease OntologyMeSH
Type:Musculoskeletal Diseases
Define:A bone inflammation disease that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage.A chronic inflammatory condition affecting the axial joints, such as the SACROILIAC JOINT and other intervertebral or costovertebral joints. It occurs predominantly in young males and is characterized by pain and stiffness of joints (ANKYLOSIS) with inflammation at tendon insertions.
Alias:Bekhterev syndrome//Bekhterev's disease//Marie-Strumpell diseaseSpondylitis, Ankylosing//Bechterew's Disease//Bechterews Disease//Marie-Struempell Disease//Marie Struempell Disease//Spondylarthritis Ankylopoietica//Spondyloarthritis Ankylopoietica//Ankylosing Spondylitis//Ankylosing Spondylarthritis//Ankylosing Spondylarthritides//Spondylarthritides, Ankylosing//Spondylarthritis, Ankylosing//Ankylosing Spondyloarthritis//Ankylosing Spondyloarthritides//Spondyloarthritides, Ankylosing//Spondyloarthritis, Ankylosing//Spondylitis Ankylopoietica//Bechterew Disease//Rheumatoid Spondylitis//Spondylitis, Rheumatoid

 

Disease Association Statistics

Total Associated ncRNA Number:16   
More Information
Causal ncRNA Number:4
Network:
Top Causal ncRNAs:
hsa_circ_0056558  (Score: 0.731059)
hsa_circ_0003307  (Score: 0.731059)
hsa_circ_0056558  (Score: 0.731059)
hsa_circ_0003307  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:31170957
Disease Name:Spondylitis, Ankylosing
Sample:blood
Dysfunction Pattern:Expression[highly expressed]
Validated Method:qRT-PCR
Description: In the present study we found that LINC00311 was upregulated in AS patients comparing to healthy controls, and upregulation of LINC00311 distinguished AS patients from healthy controls.
Causality:No
Causal Description:
Clinical-realted Application: LINC00311 expression levels were positively correlated with disease activity. Comparing to pre-treatment levels, LINC00311 expression level decreased significantly after treatment. During 2-year follow-up, patients with high levels of LINC00311 showed a significantly higher rate of rehospitalization.