Entry Detail

General Information

Database ID: LDA0016910
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:LINC-PINT
Full Name:long intergenic non-protein coding RNA, p53 induced transcript
Category:LncRNA
Species:Homo sapiens
Synonyms:LincRNA-Pint|MKLN1-AS1|PINT|PINT87aa|TISPL
Chromosome:7
Strand:-
Coordinate:
Start Site(bp):130877562End Site(bp):131109925
External Links:
Ensembl ID:ENSG00000231721
Ensembl Transcript ID:N/A
Entrez Gene:378805.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:28   
More Information
Causal Disease Number:24
Network:
Top Causal Diseases:
Stomach Neoplasms  (Score: 0.985791)
Carcinoma, Non-Small-Cell Lung  (Score: 0.985791)
Melanoma  (Score: 0.985791)
Ovarian Neoplasms  (Score: 0.985791)
Stomach Neoplasms  (Score: 0.985791)
Carcinoma, Non-Small-Cell Lung  (Score: 0.985791)
Melanoma  (Score: 0.985791)
Ovarian Neoplasms  (Score: 0.985791)
Glioblastoma  (Score: 0.731059)
Thyroid Neoplasms  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:0080850D010392
Disease Name:pemphigus foliaceusPemphigus
Category:Disease OntologyMeSH
Type:Skin and Connective Tissue Diseases
Define:A pemphigus that is characterized by blistering lesions on otherwise healthy-looking skin.Group of chronic blistering diseases characterized histologically by ACANTHOLYSIS and blister formation within the EPIDERMIS.
Alias:Pemphigus//Pemphigus Vulgaris//Pemphigus Foliaceus//Foliaceus, Pemphigus

 

Disease Association Statistics

Total Associated ncRNA Number:4   
More Information
Causal ncRNA Number:0
Network:
Top Causal ncRNAs:
More Information

 

Evidence Support

Strong Evidence:qRT-PCR//Genotyping
Weak Evidence:

 

Reference

[1] PubMed ID:33394553
Disease Name:Pemphigus
Sample:227 endemic PF patients and 194 controls
Dysfunction Pattern:Mutation(rs10228040)
Validated Method:qRT-PCR//Genotyping//Microarray
Description:Among them, the LINC-PINT SNP rs10228040*A (OR = 1.47, p = .012) was also associated with increased susceptibility for sporadic PF (OR = 2.28, p = .002). Moreover, the A+ carriers of LY86-AS1*rs12192707 mark lowest LY86-AS1 RNA levels, which might be associated with a decreasing autoimmune response.
Causality:No
Causal Description:
Clinical-realted Application: