Entry Detail

General Information

Database ID: LDA0017582
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Yes

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:USP30-AS1
Full Name:USP30 antisense RNA 1
Category:LncRNA
Species:Homo sapiens
Synonyms:-
Chromosome:12
Strand:-
Coordinate:
Start Site(bp):109052041End Site(bp):109053965
External Links:
Ensembl ID:ENSG00000256262
Ensembl Transcript ID:N/A
Entrez Gene:100131733.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:10   
More Information
Causal Disease Number:8
Network:
Top Causal Diseases:
Colonic Neoplasms  (Score: 0.731059)
Leukemia, Myeloid, Acute  (Score: 0.731059)
Uterine Cervical Neoplasms  (Score: 0.731059)
Glioblastoma  (Score: 0.731059)
Colonic Neoplasms  (Score: 0.731059)
Leukemia, Myeloid, Acute  (Score: 0.731059)
Uterine Cervical Neoplasms  (Score: 0.731059)
Glioblastoma  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:1612D001943
Disease Name:breast cancerBreast Neoplasms
Category:Disease OntologyMeSH
Type:Neoplasms
Define:A thoracic cancer that originates in the mammary gland.Tumors or cancer of the human BREAST.
Alias:breast tumor//malignant neoplasm of breast//malignant tumor of the breast//mammary cancer//mammary tumor//primary breast cancerBreast Neoplasms//Breast Neoplasm//Neoplasm, Breast//Breast Tumors//Breast Tumor//Tumor, Breast//Tumors, Breast//Neoplasms, Breast//Breast Cancer//Cancer, Breast//Mammary Cancer//Cancer, Mammary//Cancers, Mammary//Mammary Cancers//Malignant Neoplasm of Breast//Breast Malignant Neoplasm//Breast Malignant Neoplasms//Malignant Tumor of Breast//Breast Malignant Tumor//Breast Malignant Tumors//Cancer of Breast//Cancer of the Breast//Mammary Carcinoma, Human//Carcinoma, Human Mammary//Carcinomas, Human Mammary//Human Mammary Carcinomas//Mammary Carcinomas, Human//Human Mammary Carcinoma//Mammary Neoplasms, Human//Human Mammary Neoplasm//Human Mammary Neoplasms//Neoplasm, Human Mammary//Neoplasms, Human Mammary//Mammary Neoplasm, Human//Breast Carcinoma//Breast Carcinomas//Carcinoma, Breast//Carcinomas, Breast

 

Disease Association Statistics

Total Associated ncRNA Number:1186   
More Information
Causal ncRNA Number:766
Network:
Top Causal ncRNAs:
MILIP  (Score: 1)
GAS5  (Score: 1)
MILIP  (Score: 1)
H19  (Score: 1)
CDKN2B-AS1  (Score: 1)
DANCR  (Score: 1)
AFAP1-AS1  (Score: 1)
CDKN2B-AS1  (Score: 1)
NEAT1  (Score: 1)
circHIPK3  (Score: 1)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:33614483
Disease Name:Breast Neoplasms
Sample:TCGA and breast cancer cells
Dysfunction Pattern:Expression [highly expressed]
Validated Method:qRT-PCR
Description:The qRT-PCR identified 5 lncRNAs with significantly differential expression in breast cancer cells based on the 9 lncRNAs of the prognostic model, and the results were consistent with the tissues.
Causality:No
Causal Description:
Clinical-realted Application:In order to further explore the prognostic value of the 9 lncRNAs, the Kaplan Meier curve was built to confirm the relationship between these lncRNAs and OS. In our analysis, a total of 6 of the 9 lncRNAs (USP30-AS1, ST7-AS1, VPS9D1-AS1, OTUB6DB-AS1, LINC01087, and MAPT-AS1) were identified. The results indicated that the 6 autophagy-related lncRNAs were correlated to the OS in breast cancer patients