Entry Detail

General Information

Database ID: LDA0017622
Species: Homo sapiens
Confidence Score: 0.548294
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Yes

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:UCA1
Full Name:urothelial cancer associated 1
Category:LncRNA
Species:Homo sapiens
Synonyms:CUDR|LINC00178|NCRNA00178|UCAT1|onco-lncRNA-36
Chromosome:19
Strand:+
Coordinate:
Start Site(bp):15828947End Site(bp):15836321
External Links:
Ensembl ID:ENSG00000214049
Ensembl Transcript ID:N/A
Entrez Gene:652995.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:94   
More Information
Causal Disease Number:76
Network:
Top Causal Diseases:
Squamous Cell Carcinoma of Head and Neck  (Score: 1)
Osteosarcoma  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Stomach Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Uterine Cervical Neoplasms  (Score: 1)
Glioma  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Stomach Neoplasms  (Score: 1)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:D005770
Disease Name:Gastrointestinal Neoplasms
Category:MeSH
Type:Neoplasms
Define:Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL.
Alias:Gastrointestinal Neoplasms//Gastrointestinal Neoplasm//Neoplasm, Gastrointestinal//Neoplasms, Gastrointestinal//Cancer of Gastrointestinal Tract//Gastrointestinal Tract Cancer//Gastrointestinal Tract Cancers//Cancer of the Gastrointestinal Tract//Gastrointestinal Cancer//Cancer, Gastrointestinal//Cancers, Gastrointestinal//Gastrointestinal Cancers

 

Disease Association Statistics

Total Associated ncRNA Number:6   
More Information
Causal ncRNA Number:0
Network:
Top Causal ncRNAs:
More Information

 

Evidence Support

Strong Evidence:
Weak Evidence:Meta-analysis

 

Reference

[1] PubMed ID:31612385
Disease Name:Gastrointestinal Neoplasms
Sample:
Dysfunction Pattern:Expression[highly expressed]
Validated Method:Meta-analysis
Description:It is suggested that UCA1 abundance may serve as a reliable predictive factor for poor prognosis in patients with digestive system malignancies.
Causality:No
Causal Description:
Clinical-realted Application:A significant association was observed between UCA1 abundance and poor overall survival (OS), and shorter disease-free survival (DFS) for patients with digestive system malignancies, with pooled HR of 2.07 (95%CI: 1.74-2.47), and of 2.50 (95%CI: 1.62-3.86).