Entry Detail

General Information

Database ID: LDA0017653
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Yes

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:UCA1
Full Name:urothelial cancer associated 1
Category:LncRNA
Species:Homo sapiens
Synonyms:CUDR|LINC00178|NCRNA00178|UCAT1|onco-lncRNA-36
Chromosome:19
Strand:+
Coordinate:
Start Site(bp):15828947End Site(bp):15836321
External Links:
Ensembl ID:ENSG00000214049
Ensembl Transcript ID:N/A
Entrez Gene:652995.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:94   
More Information
Causal Disease Number:76
Network:
Top Causal Diseases:
Squamous Cell Carcinoma of Head and Neck  (Score: 1)
Osteosarcoma  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Stomach Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Uterine Cervical Neoplasms  (Score: 1)
Glioma  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Stomach Neoplasms  (Score: 1)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:263D007680
Disease Name:kidney cancerKidney Neoplasms
Category:Disease OntologyMeSH
Type:Neoplasms
Define:A urinary system cancer that is located_in the kidney.Tumors or cancers of the KIDNEY.
Alias:malignant neoplasm of kidney except pelvis//malignant tumour of kidney//renal cancerKidney Neoplasms//Kidney Neoplasm//Neoplasm, Kidney//Renal Neoplasms//Neoplasm, Renal//Neoplasms, Renal//Renal Neoplasm//Neoplasms, Kidney//Cancer of Kidney//Kidney Cancers//Renal Cancer//Cancer, Renal//Cancers, Renal//Renal Cancers//Cancer of the Kidney//Kidney Cancer//Cancer, Kidney//Cancers, Kidney

 

Disease Association Statistics

Total Associated ncRNA Number:20   
More Information
Causal ncRNA Number:16
Network:
Top Causal ncRNAs:
LINC01852-201  (Score: 0.731059)
EGFR-AS1  (Score: 0.731059)
DUXAP9  (Score: 0.731059)
circTXNDC11  (Score: 0.731059)
hsa_circ_0065217  (Score: 0.731059)
circCYP24A1  (Score: 0.731059)
circKL  (Score: 0.731059)
TCL6  (Score: 0.731059)
LINC01852-201  (Score: 0.731059)
EGFR-AS1  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR//Luciferase Report Assay//Western Blot
Weak Evidence:

 

Reference

[1] PubMed ID:31996265
Disease Name:Kidney Neoplasms
Sample:renal cancer cell lines
Dysfunction Pattern:regulation[miR-182-5p/DLL4 axis]
Validated Method:qRT-PCR//Luciferase Report Assay//Western Blot
Description: In this study, we found that UCA1 was significantly up-regulated in renal cancer. UCA1-miR-182-5p-DLL4 axis is involved in proliferation and progression of renal cancer.
Causality:No
Causal Description:
Clinical-realted Application: Moreover, increased UCA1 expression was positively correlated with differentiation and advanced TNM stage.