Entry Detail


General Information

Database ID: LDA0017765
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:THRIL
Full Name:TNF and HNRNPL related immunoregulatory long non-coding RNA
Category:LncRNA
Species:Homo sapiens
Synonyms:BRI3BP-AS1|BRI3BPAS1|Linc1992|TCONS_00020260
Chromosome:12
Strand:-
Coordinate:
Start Site(bp):125025443End Site(bp):125027423
External Links:
Ensembl ID:ENSG00000280634
Ensembl Transcript ID:N/A
Entrez Gene:102659353.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:22   
More Information
Causal Disease Number:10
Network:
Top Causal Diseases:
Arthritis, Rheumatoid  (Score: 0.999893)
Arthritis, Rheumatoid  (Score: 0.999893)
Osteosarcoma  (Score: 0.731059)
Coronary Disease  (Score: 0.731059)
Lung Injury  (Score: 0.731059)
Cerebral Ischaemia/Reperfusion Injury  (Score: 0.731059)
Osteosarcoma  (Score: 0.731059)
Coronary Disease  (Score: 0.731059)
Lung Injury  (Score: 0.731059)
Cerebral Ischaemia/Reperfusion Injury  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:3393D003327
Disease Name:coronary artery diseaseCoronary Disease
Category:Disease OntologyMeSH
Type:Cardiovascular Diseases
Define:An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Alias:CHD//Coronary disease//coronary arteriosclerosis//coronary heart diseaseCoronary Disease//Coronary Diseases//Disease, Coronary//Diseases, Coronary//Coronary Heart Disease//Coronary Heart Diseases//Disease, Coronary Heart//Diseases, Coronary Heart//Heart Disease, Coronary//Heart Diseases, Coronary

 

Disease Association Statistics

Total Associated ncRNA Number:44   
More Information
Causal ncRNA Number:10
Network:
Top Causal ncRNAs:
EZR-AS1  (Score: 0.731059)
LOXL1-AS1  (Score: 0.731059)
SENCR  (Score: 0.731059)
circCHFR  (Score: 0.731059)
THRIL  (Score: 0.731059)
EZR-AS1  (Score: 0.731059)
LOXL1-AS1  (Score: 0.731059)
SENCR  (Score: 0.731059)
circCHFR  (Score: 0.731059)
THRIL  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:31944373
Disease Name:Coronary Disease
Sample:blood
Dysfunction Pattern:Expression[highly expressed]
Validated Method:qRT-PCR
Description:Both before and after adjustment by age/gender, lncRNA THRIL was increased in CHD patients compared with control subjects (both P < .001), and it well predicted enhanced CHD risk by receiver operating characteristic curves.
Causality:No
Causal Description:
Clinical-realted Application: