Entry Detail


General Information

Database ID: LDA0017888
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:TUG1
Full Name:taurine up-regulated 1
Category:LncRNA
Species:Homo sapiens
Synonyms:LINC00080|NCRNA00080|TI-227H
Chromosome:22
Strand:+
Coordinate:
Start Site(bp):30969265End Site(bp):30979395
External Links:
Ensembl ID:ENSG00000253352
Ensembl Transcript ID:N/A
Entrez Gene:55000.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:106   
More Information
Causal Disease Number:66
Network:
Top Causal Diseases:
Prostatic Neoplasms  (Score: 1)
Osteosarcoma  (Score: 1)
Prostatic Neoplasms  (Score: 1)
Osteosarcoma  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Leukemia, Myeloid, Acute  (Score: 0.999998)
Leukemia, Myeloid, Acute  (Score: 0.999998)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:3312D001714
Disease Name:bipolar disorderBipolar Disorder
Category:Disease OntologyMeSH
Type:Mental Disorders
Define:A mood disorder that involves alternating periods of mania and depression.A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
Alias:Manic Bipolar Affective disorder//Manic Depressive disorder//Manic bipolar I disorder//bipolar depression//bipolar disorder manic phase//manic depression//manic disorder//mixed bipolar disorderBipolar Disorder//Bipolar Disorders//Disorder, Bipolar//Psychosis, Manic-Depressive//Psychosis, Manic Depressive//Psychoses, Manic-Depressive//Psychoses, Manic Depressive//Manic-Depressive Psychosis//Manic Depressive Psychosis//Bipolar Mood Disorder//Bipolar Mood Disorders//Disorder, Bipolar Mood//Mood Disorder, Bipolar//Affective Psychosis, Bipolar//Bipolar Affective Psychosis//Psychoses, Bipolar Affective//Psychosis, Bipolar Affective//Bipolar Disorder Type 1//Type 1 Bipolar Disorder//Manic Depression//Depression, Manic//Depressions, Manic//Depression, Bipolar//Bipolar Depression//Bipolar Disorder Type 2//Type 2 Bipolar Disorder//Manic Disorder//Disorder, Manic//Manic Disorders

 

Disease Association Statistics

Total Associated ncRNA Number:10   
More Information
Causal ncRNA Number:0
Network:
Top Causal ncRNAs:
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:30772744
Disease Name:Bipolar Disorder
Sample:blood
Dysfunction Pattern:Expression[highly expressed]
Validated Method:qRT-PCR
Description:CCAT2, TUG1 and PANDA were up-regulated in total BD patients compared with total healthy subjects (P values = 0.006, <0.001 and 0.004 respectively) while OIP5-AS1 was down-regulated (P = 0.001).
Causality:No
Causal Description:
Clinical-realted Application: