Entry Detail

General Information

Database ID: LDA0018380
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:PANDAR
Full Name:promoter of CDKN1A antisense DNA damage activated RNA
Category:LncRNA
Species:Homo sapiens
Synonyms:PANDA
Chromosome:6
Strand:-
Coordinate:
Start Site(bp):36673621End Site(bp):36675126
External Links:
Ensembl ID:ENSG00000281450
Ensembl Transcript ID:N/A
Entrez Gene:101154753.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:22   
More Information
Causal Disease Number:12
Network:
Top Causal Diseases:
Squamous Cell Carcinoma of Head and Neck  (Score: 0.985791)
Squamous Cell Carcinoma of Head and Neck  (Score: 0.985791)
Breast Neoplasms  (Score: 0.959542)
Breast Neoplasms  (Score: 0.959542)
Glioma  (Score: 0.731059)
Lung Neoplasms  (Score: 0.731059)
Thyroid Neoplasms  (Score: 0.731059)
Esophageal Squamous Cell Carcinoma  (Score: 0.731059)
Glioma  (Score: 0.731059)
Lung Neoplasms  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:9351D003920
Disease Name:diabetes mellitusDiabetes Mellitus
Category:Disease OntologyMeSH
Type:Nutritional and Metabolic Diseases
Define:A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
Alias:Diabetes Mellitus

 

Disease Association Statistics

Total Associated ncRNA Number:52   
More Information
Causal ncRNA Number:10
Network:
Top Causal ncRNAs:
HAND2-AS1  (Score: 0.731059)
LINC-PINT  (Score: 0.731059)
AQP4-AS1  (Score: 0.731059)
PRINS  (Score: 0.731059)
TINCR  (Score: 0.731059)
HAND2-AS1  (Score: 0.731059)
LINC-PINT  (Score: 0.731059)
AQP4-AS1  (Score: 0.731059)
PRINS  (Score: 0.731059)
TINCR  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:30139387
Disease Name:Diabetes Mellitus
Sample:peripheral blood mononuclear cells
Dysfunction Pattern:Expression[highly expressed]
Validated Method:qRT-PCR
Description:Compared to control subjects, expression levels of lncRNAs in PBMCs from type 2 diabetes patients showed significantly (p < 0.05) increased levels of HOTAIR, MEG3, LET, MALAT1, MIAT, CDKN2BAS1/ANRIL, XIST, PANDA, GAS5, Linc-p21, ENST00000550337.1, PLUTO, and NBR2. In contrast, lncRNA expression patterns of THRIL and SALRNA1 were significantly (p < 0.05) decreased in patients with T2DM compared to control subjects.
Causality:No
Causal Description:
Clinical-realted Application: