Entry Detail

General Information

Database ID: LDA0018393
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:NORAD
Full Name:non-coding RNA activated by DNA damage
Category:LncRNA
Species:Homo sapiens
Synonyms:LINC00657
Chromosome:20
Strand:-
Coordinate:
Start Site(bp):36045618End Site(bp):36050960
External Links:
Ensembl ID:ENSG00000260032
Ensembl Transcript ID:N/A
Entrez Gene:647979.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:50   
More Information
Causal Disease Number:38
Network:
Top Causal Diseases:
Stomach Neoplasms  (Score: 1)
Prostatic Neoplasms  (Score: 1)
Squamous Cell Carcinoma of Head and Neck  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Carcinoma, Non-Small-Cell Lung  (Score: 1)
Stomach Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Prostatic Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:3393D003327
Disease Name:coronary artery diseaseCoronary Disease
Category:Disease OntologyMeSH
Type:Cardiovascular Diseases
Define:An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Alias:CHD//Coronary disease//coronary arteriosclerosis//coronary heart diseaseCoronary Disease//Coronary Diseases//Disease, Coronary//Diseases, Coronary//Coronary Heart Disease//Coronary Heart Diseases//Disease, Coronary Heart//Diseases, Coronary Heart//Heart Disease, Coronary//Heart Diseases, Coronary

 

Disease Association Statistics

Total Associated ncRNA Number:44   
More Information
Causal ncRNA Number:10
Network:
Top Causal ncRNAs:
EZR-AS1  (Score: 0.731059)
LOXL1-AS1  (Score: 0.731059)
SENCR  (Score: 0.731059)
circCHFR  (Score: 0.731059)
THRIL  (Score: 0.731059)
EZR-AS1  (Score: 0.731059)
LOXL1-AS1  (Score: 0.731059)
SENCR  (Score: 0.731059)
circCHFR  (Score: 0.731059)
THRIL  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR//ELISA
Weak Evidence:

 

Reference

[1] PubMed ID:36319574
Disease Name:Coronary Disease
Sample:CHD patients
Dysfunction Pattern:Expression(highly expressed)
Validated Method:qRT-PCR//ELISA
Description: Lnc-NORAD was highest in CHD patients, followed by DCs, and lowest in HCs (p < 0.001). In CHD patients, lnc-NORAD was positively linked with Gensini score (p = 0.001). Meanwhile, lnc-NORAD was positively linked to C-reactive protein (p = 0.023), tumor necrosis factor-alpha (p = 0.016), interleukin (IL)-6 (p = 0.003), IL-8 (P = 0.018), and IL-17A (p = 0.029).
Causality:No
Causal Description:
Clinical-realted Application: